Evidence map›Paper›PMID 28386173›Full record

ArticleSaudi journal of biological sciences2017

Analysis on regulatory network linked to Hpa gene in invasion and metastasis of colon cancer.

Lei Zhang, Huili Wu, Xingguo Xiao, Kunkun Li, Yang Zhang, Li Zhang, Tingyu Wen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lei ZhangDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Huili WuDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Xingguo XiaoDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Kunkun LiDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Yang ZhangDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Li ZhangDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Tingyu WenDepartment of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, No.195, Tongbai Road, Zhongyuan District, Zhengzhou, Henan Province, China.
Zhengzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our purpose was to discuss the biological function of Hpa gene and its regulatory network in invasion and metastasis of colon cancer. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes database were used to perform functional annotation and pathway analysis on Hpa gene. Gene Ontology analysis results showed that Hpa plays a significant role in cellular component, molecular function and biological process; and combined with Kyoto Encyclopedia of Genes and Genomes database, regulatory network of angiogenesis of colon cancer was drawn out. Through analysis of regulatory network linked to angiogenesis in invasion and metastasis of colon cancer, the study lays foundation for further prevention, diagnosis and treatment of colon cancer.

Indexed as

AngiogenesisGO analysisHpa geneInvasion and metastasis of colon cancerNetwork pathway

Identifiers

PMID28386173
PMCPMC5372369
OpenAlexW2581871052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.