Evidence map›Paper›PMID 28386165›Full record

ArticleCanadian respiratory journal2017

Effect of Antipyretic Therapy on Mortality in Critically Ill Patients with Sepsis Receiving Mechanical Ventilation Treatment.

Sheng Ye, Dan Xu, Chenmei Zhang, Mengyao Li, Yanyi Zhang

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Canadian respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04227652 nacompletednot on this map

Control of Fever in Septic Patients

TypeinterventionalSponsorUniversity Hospital OstravaRan2013 to 2019Enrolled140ConditionsSepsis, Severe Sepsis, Septic ShockArmsIbuprofen administration
NCT06061575 phase4completednot on this mapstarted 2023, after this paper: background citation

Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients: A Randomized Double-Blind Controlled Study

TypeinterventionalSponsorAnkara City Hospital BilkentRan2023 to 2024Enrolled113ConditionsSepsis, Acetaminophen, Fever, IbuprofenArmsAcetaminophen, Ibuprofen
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. The poikilothermic hypothesis of sepsis.Critical care (London, England) · 2026
    Review
  3. Fever in Sepsis Revisited: Is a Little Heat What We Need?Open forum infectious diseases · 2025
    Review
  4. Article
  5. Review
  6. Ten tips on fever.Intensive care medicine · 2023
    Article
  7. Temperature control in sepsis.Frontiers in medicine · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sheng YePediatric Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Dan XuPediatric Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Chenmei ZhangPediatric Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Mengyao LiPediatric Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Yanyi ZhangPsychological Department, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.ORCID 0000-0001-5238-1712
Children's Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overAntipyreticsBostonCritical IllnessFemaleFeverHumansMaleMiddle AgedSepsisAntipyretics

Identifiers

PMID28386165
PMCPMC5366196
OpenAlexW2594000299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.