Evidence map›Paper›PMID 28386096›Full record

ArticleScientific reports2017

A Facile Method to Probe the Vascular Permeability of Nanoparticles in Nanomedicine Applications.

Yan Teck Ho, Giulia Adriani, Sebastian Beyer, Phan-Thien Nhan, Roger D Kamm, James Chen Yong Kah

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 66 citations in OpenAlex.

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  8. Acoustofluidic Engineering of Functional Vessel-on-a-Chip.ACS biomaterials science & engineering · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Integration of immune cells in organs-on-chips: a tutorial.Frontiers in bioengineering and biotechnology · 2023
    Review
  13. Article
  14. In Vitro Models of Biological Barriers for Nanomedical Research.International journal of molecular sciences · 2022
    Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Yan Teck HoNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
Giulia AdrianiBioSyM Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.ORCID http://orcid.org/0000-0002-7505-1668
Sebastian BeyerBioSyM Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Phan-Thien NhanNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
Roger D KammBioSyM Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore. rdkamm@mit.edu.
James Chen Yong KahNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore. biekahj@nus.edu.sg.ORCID http://orcid.org/0000-0002-2247-6929
National University of Singapore · SGSingapore-MIT Alliance for Research and Technology · SGFederal Institute For Materials Research and Testing · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effectiveness of nanoparticles (NP) in nanomedicine depends on their ability to extravasate from vasculature towards the target tissue. This is determined by their permeability across the endothelial barrier. Unfortunately, a quantitative study of the diffusion permeability coefficients (P

Indexed as

Capillary PermeabilityNanomedicineNanoparticlesAlgorithmsAngiotensin ICells, CulturedCyclic AMPDextransDiffusionHumansHuman Umbilical Vein Endothelial CellsLab-On-A-Chip DevicesModels, BiologicalPolystyrenesAngiotensin ICyclic AMPDextransPolystyrenes

Identifiers

PMID28386096
PMCPMC5429672
OpenAlexW2600890536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.