Evidence map›Paper›PMID 28386020›Full record

ArticleJournal of cell science2017

Evolution of the endomembrane systems of trypanosomatids - conservation and specialisation.

Divya Venkatesh, Cordula Boehm, Lael D Barlow, Nerissa N Nankissoor, Amanda O'Reilly, Steven Kelly, Joel B Dacks, Mark C Field

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Evolution of factors shaping the endoplasmic reticulum.Traffic (Copenhagen, Denmark) · 2022
    Article
  3. Article
  4. The Rab7 subfamily acrossSmall GTPases · 2020
    Article
  5. Longin R-SNARE is retrieved from the plasma membrane by ANTH domain-containing proteins inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Divya VenkateshWellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.
Cordula BoehmWellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.
Lael D BarlowDepartment of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Nerissa N NankissoorDepartment of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Amanda O'ReillyDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PQ, UK.
Steven KellyDepartment of Plant Sciences, University of Oxford, Oxford OX1 6JP, UK.
Joel B DacksDepartment of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.
Mark C FieldWellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK mfield@mac.com.ORCID 0000-0002-4866-2885
University of Alberta · CAUniversity of Dundee · GBUniversity of Cambridge · GBUniversity of Oxford · GB

Funding

Wellcome Trust 203134/Z/16/Z
6 · The paper itself

Abstract

Parasite surfaces support multiple functions required for survival within their hosts, and maintenance and functionality of the surface depends on membrane trafficking. To understand the evolutionary history of trypanosomatid trafficking, where multiple lifestyles and mechanisms of host interactions are known, we examined protein families central to defining intracellular compartments and mediating transport, namely Rabs, SNAREs and RabGAPs, across all available Euglenozoa genomes. Bodonids possess a large trafficking repertoire, which is mainly retained by the

Indexed as

Biological EvolutionEuglenozoaHost-Pathogen InteractionsTrypanosoma cruziCell MembraneConserved SequenceEndocytosisExocytosisGenomeGTPase-Activating ProteinsHost SpecificityProtein TransportProteomicsProtozoan Proteinsrab GTP-Binding ProteinsSNARE ProteinsGTPase-Activating ProteinsProtozoan Proteinsrab GTP-Binding ProteinsSNARE ProteinsMolecular evolutionProteomicsRabSNARETBC domainTraffickingTrypanosoma

Identifiers

PMID28386020
PMCPMC5399786
OpenAlexW2605291658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.