ArticleScience (New York, N.Y.)2017
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 258 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
258citing papers in PubMed, 1 pooled it
37.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
258 citing papers in PubMed, 1 synthesis or guideline pooled it, 449 citations in OpenAlex.
- Viruses and celiac disease: what do we know ?Clinical and experimental medicine · 2023Pooled it
- The enteric DNA virome differs in infants at risk for atopic disease.Gut microbes · 2026Article
- T cell fate is dictated by different antigen-presenting cells in response to dietary versus gut epithelial self-antigen.Immunity · 2026Article
- Article
- Beyond Bacteria: The Emerging Role of the Gut Virome and Mycobiome in Celiac Disease.Nutrients · 2026Review
- The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten.Nature immunology · 2026Article
- Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression.Cell reports · 2026Article
- The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of gut health.Nature reviews. Gastroenterology & hepatology · 2026Article
- Unveiling the viral dimension: The paediatric gut virome as a key modulator of gastrointestinal metabolic, and neurodevelopmental health.World journal of virology · 2026Review
- Long-term effects of reovirus strain T3D on the myocardium.Microbiology spectrum · 2026Article
- A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- m6A RNA methylation modulates antiviral response in celiac disease.Genes and immunity · 2026Article
- Article
- From gluten to therapeutics: molecular mechanisms of celiac disease and emerging alternatives to the gluten-free diet.Frontiers in pharmacology · 2026Review
- Dendritic Cells in the Gastrointestinal System: Division of Labor, Plasticity, and Niche-Specific Adaptation.Immunological reviews · 2026Review
- Immune cell dynamics and mechanisms of epithelial injury in celiac disease.Frontiers in immunology · 2026Review
- Innate immune dysregulation in celiac disease and refractory celiac disease: mechanisms, management and emerging therapies.Frontiers in immunology · 2026Review
- Gene-Environment Interactions in Celiac Disease: The Role of the Intestinal Epithelium.Lifestyle genomics · 2026Review
- Annexin A2 stabilizes the endoplasmic reticulum and actin cytoskeleton and influences the formation of reovirus factories.Journal of virology · 2025Article
198 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
34 authors at 8 institutions in 4 countries.
Romain BouziatDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-7649-7306
Reinhard HinterleitnerDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-6518-108X
Judy J BrownDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-2608-3169
Jennifer E Stencel-BaerenwaldDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Mine IkizlerElizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Toufic MayassiDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-5458-1352
Marlies MeiselDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Sangman M KimDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-8204-0393
Valentina DiscepoloDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-6158-0545
Andrea J PruijssersElizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Jordan D ErnestDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-0857-217X
Jason A IskarpatyotiElizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Léa M M CostesDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Ian LawrenceDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4032-5611
Brad A PalanskiDepartment of Chemistry, Stanford University, Stanford, CA, USA.ORCID 0000-0002-4049-4274
Mukund VarmaDivision of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-9254-1247
Matthew A ZurenskiDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Solomiia KhomandiakElizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Nicole McAllisterDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-2641-4813
Pavithra AravamudhanElizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Karl W BoehmeElizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-2691-9763
Fengling HuDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Janneke N SamsomLaboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center Rotterdam-Sophia Children's Hospital, Rotterdam, Netherlands.
Hans-Christian ReineckerDivision of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8283-644X
Sonia S KupferDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Stefano GuandaliniUniversity of Chicago Celiac Disease Center, University of Chicago, Chicago, IL, USA.
Carol E SemradDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Valérie AbadieDepartment of Microbiology, Infectiology, and Immunology, University of Montreal, and the Centre Hospitalier Universitaire (CHU) Sainte-Justine Research Center, Montreal, Quebec, Canada.
Chaitan KhoslaDepartment of Chemistry, Stanford University, Stanford, CA, USA.
Luis B BarreiroDepartment of Genetics, CHU Sainte-Justine Research Center, Montreal, Quebec, Canada.ORCID 0000-0001-9456-367X
Ramnik J XavierDivision of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5630-5167
Aylwin NgDivision of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Terence S DermodyDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA. bjabri@bsd.uchicago.edu terence.dermody@chp.edu.ORCID 0000-0003-1853-8741
Bana JabriDepartment of Medicine, University of Chicago, Chicago, IL, USA. bjabri@bsd.uchicago.edu terence.dermody@chp.edu.ORCID 0000-0001-7427-4424
University of Chicago · USVanderbilt University Medical Center · USBroad Institute · USCentre Hospitalier Universitaire Sainte-Justine · CAErasmus MC · NLStanford University · USHarvard University · USUniversity of Pittsburgh · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8MVIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1MPilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3MULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI LIU, CAMBRIAN YANGSHAO · 1990 to 2025
$29.8MVanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9MINTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007090 · NIAID · UNIVERSITY OF CHICAGO · PI Peter Aidan Savage · 1985 to 2026
$11.7MRole of Transglutaminase 2 in Celiac SprueR01DK063158 · NIDDK · STANFORD UNIVERSITY · PI CHAITAN KHOSLA · 2003 to 2026
$11.2MInnate and adaptive immunity in celiac diseaseR01DK067180 · NIDDK · UNIVERSITY OF CHICAGO · PI JABRI, BANA · 2005 to 2024
$8.5MVanderbilt Mouse Metabolic Phenotyping CenterU2CDK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2016 to 2021
$6.3MInnate Immune Defense Mechanisms in the IntestineR01AI113333 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI REINECKER, HANS-CHRISTIAN · 2014 to 2025
$5.7MViral infections and celiac disease pathogenesisR01DK098435 · NIDDK · UNIVERSITY OF CHICAGO · PI DERMODY, TERENCE S., JABRI, BANA · 2014 to 2022
$5.4MImmunology of Infectious DiseaseT32AI060525 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JoAnne L. Flynn · 2005 to 2026
$5.3MNCI NIH HHS P30 CA014599NCI NIH HHS P30 CA068485NIAID NIH HHS R01 AI038296NIAID NIH HHS R01 AI113333NIAID NIH HHS T32 AI007090NIAID NIH HHS T32 AI060525NIDDK NIH HHS F31 DK108562NIDDK NIH HHS P30 DK042086NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK063158NIDDK NIH HHS R01 DK067180NIDDK NIH HHS R01 DK068181NIDDK NIH HHS R01 DK091247NIDDK NIH HHS R01 DK098435NIDDK NIH HHS R01 DK100619NIDDK NIH HHS U24 DK059637NIDDK NIH HHS U2C DK059637
Abstract
Viral infections have been proposed to elicit pathological processes leading to the initiation of T helper 1 (T
Indexed as
AnimalsAntigensCeliac DiseaseDietDisease Models, AnimalGenetic EngineeringGlutensHumansImmune ToleranceInflammationInterferon Regulatory Factor-1Interferon Type IIntestinesMiceMice, Inbred C57BLMice, TransgenicAntigensGlutensInterferon Regulatory Factor-1Interferon Type IReceptor, Interferon alpha-beta
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.