Evidence map›Paper›PMID 28385894›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2017

Regional variations in ambulatory care and incidence of cardiovascular events.

Jack V Tu, Anna Chu, Laura Maclagan, Peter C Austin, Sharon Johnston, Dennis T Ko, Ingrid Cheung, Clare L Atzema, Gillian L Booth, R Sacha Bhatia and 11 more

Registry-linked trialAbstract readMulticenter Study

PubMed Full text at PMC Publisher

In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04067297 (Using Big Data to Conduct Innovative Cardiovascular Clinical Trials), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

33citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04067297 naactive not recruitingnot on this mapstarted 2019, after this paper: background citation

Using Big Data to Conduct Innovative Cardiovascular Clinical Trials: The Community Heart Outcomes Improvement and Cholesterol Education Study (CHOICES)

TypeinterventionalSponsorInstitute for Clinical Evaluative SciencesRan2019 to 2027Enrolled500,000ConditionsCardiovascular Diseases, Cardiovascular Risk Factor, DyslipidemiasArmsLipid management toolbox

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2018 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018
Guideline
Understanding Burn Injury Management: A Cross-Sectional Survey of Physicians Working in Northern Ontario Emergency Departments.Cureus · 2026
Article
Barriers to Accessing Vascular Surgery in Northern, Rural, and Remote Canadian Communities.CJC open · 2026
Review
Sex Differences in Self-Rated Health and Cardiovascular Disease Events.JAMA network open · 2026
Article
Impact of Zero Coronary Artery Calcium Scoring on Downstream Cardiac Testing and Cardiac Outcomes Compared With No Testing.CJC open · 2025
Article
Sex-based analysis of NSTEMI processes of care and outcomes by hospital: a nationwide cohort study.European heart journal. Quality of care & clinical outcomes · 2024
Article
Postoperative outcomes among Northern versus Southern Ontario patients undergoing common intermediate- to high-risk elective surgeries: a population-based cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
Article
Distribution of catheterisation laboratories in Indonesia 2017-2022: a nationwide survey.The Lancet regional health. Southeast Asia · 2024
Article
Geographic access to pediatric neurosurgeons in the USA: an analysis of sociodemographic factors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
Article
The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 7: Sex, Gender, and the Social Determinants of Health.CJC open · 2024
Review
Geographic Disparities in Access to Neurologists and Multiple Sclerosis Care in the United States.Neurology · 2024
Article
Regional variations in vaccination against COVID-19 in Germany.PloS one · 2024
Article
Social Determinants of Stroke Hospitalization and Mortality in United States' Counties.Journal of clinical medicine · 2022
Article
Predicting hospitalisations related to ambulatory care sensitive conditions with machine learning for population health planning: derivation and validation cohort study.BMJ open · 2022
Article
Patient, physician and geographic predictors of cardiac stress testing strategy in Ontario, Canada: a population-based study.BMJ open · 2022
Article
Leading POCT Networks: Operating POCT Programs Across Multiple Sites Involving Vast Geographical Areas and Rural Communities.EJIFCC · 2021
Review
The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women-Chapter 2: Scope of the Problem.CJC open · 2021
Review
Strategies for enhancing the initiation of cholesterol lowering medication among patients at high cardiovascular disease risk: a qualitative descriptive exploration of patient and general practitioners' perspectives on a facilitated relay intervention in Alberta, Canada.BMJ open · 2020
Article
Use of Cardiac Noninvasive Testing After Emergency Department Discharge: Association of Hospital Network Testing Intensity and Outcomes in Ontario, Canada.Journal of the American Heart Association · 2020
Article
Patient- and Physician-Level Factors Associated With Adherence to C-CHANGE Recommendations in Primary Care Settings in Ontario.CJC open · 2020
Article

4 · The record

Corrections and comments

Commented on by
Geographic location as a modifiable cardiac risk factor.2017
Commented on by
A comprehensive approach needed to address regional variation.2017
Commented on by
Response to: "A comprehensive approach needed to address regional variation".2017

5 · Who and what money

Authors and funding

21 authors.

Jack V TuInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont. tu@ices.on.ca.

Anna ChuInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Laura MaclaganInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Peter C AustinInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Sharon JohnstonInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Dennis T KoInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Ingrid CheungInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Clare L AtzemaInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Gillian L BoothInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

R Sacha BhatiaInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Douglas S LeeInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Cynthia A JackeviciusInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Moira K KapralInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Karen TuInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Harindra C WijeysunderaInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

David A AlterInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Jacob A UdellInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Douglas G ManuelInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Prosanta MondalInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

William HoggInstitute for Clinical Evaluative Sciences (J. Tu, Chu, Maclagan, Austin, Ko, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel, Mondal), Toronto, Ont.; Schulich Heart Centre, Sunnybrook Health Sciences Centre (J. Tu, Ko, Wijeysundera), Toronto, Ont.; University of Toronto (J. Tu, Chu, Austin, Ko, Cheung, Atzema, Booth, Bhatia, Lee, Jackevicius, Kapral, K. Tu, Wijeysundera, Alter, Udell, Manuel), Toronto, Ont.; Bruyère Research Institute (Johnston, Hogg), Ottawa, Ont.; University of Ottawa (Johnston, Hogg), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Atzema), Toronto, Ont.; St. Michael's Hospital (Booth), Toronto, Ont.; Women's College Hospital Institute for Health Systems Solutions and Virtual Care (Bhatia), Toronto, Ont.; University Health Network (Bhatia, Lee, Jackevicius, Kapral, K. Tu, Alter, Udell), Toronto, Ont.; Western University of Health Sciences (Jackevicius), Pomona, Calif.; Women's College Hospital (Udell), Toronto, Ont.; Ottawa Hospital Research Institute (Manuel), Ottawa, Ont.

Cardiovascular Health in Ambulatory Care Research Team (CANHEART)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVariations in the prevalence of traditional cardiac risk factors only partially account for geographic variations in the incidence of cardiovascular disease. We examined the extent to which preventive ambulatory health care services contribute to geographic variations in cardiovascular event rates.

methodsWe conducted a cohort study involving 5.5 million patients aged 40 to 79 years in Ontario, Canada, with no hospital stays for cardiovascular disease as of January 2008, through linkage of multiple population-based health databases. The primary outcome was the occurrence of a major cardiovascular event (myocardial infarction, stroke or cardiovascular-related death) over the following 5 years. We compared patient demographics, cardiac risk factors and ambulatory health care services across the province's 14 health service regions, known as Local Health Integration Networks (LHINs), and evaluated the contribution of these variables to regional variations in cardiovascular event rates.

resultsCardiovascular event rates across LHINs varied from 3.2 to 5.7 events per 1000 person-years. Compared with residents of high-rate LHINs, those of low-rate health regions received physician services more often (e.g., 4.2 v. 3.5 mean annual family physician visits,

interpretationPreventive ambulatory health care services were provided more frequently in health regions with lower cardiovascular event rates. Health system interventions to improve equitable access to preventive care might improve cardiovascular outcomes.

Indexed as

AdultAgedAmbulatory CareCohort StudiesDemographyDiabetes MellitusDrug PrescriptionsDyslipidemiasFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHydroxymethylglutaryl CoA ReductasesHypertensionIncidenceMaleMiddle AgedHydroxymethylglutaryl-CoA Reductase InhibitorsHydroxymethylglutaryl CoA Reductases

Identifiers

PMID28385894

DOI10.1503/cmaj.160823

PMCPMC5378509

What OpenQuestion holds

Texttitle and abstract

Read underepoch 390

Registered trials

NCT04067297ClinicalTrials.gov

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.