Evidence map›Paper›PMID 28385890›Full record

ArticleThe Journal of biological chemistry2017

Ziploc-ing the structure 2.0: Endoplasmic reticulum-resident peptidyl prolyl isomerases show different activities toward hydroxyproline.

Yoshihiro Ishikawa, Kazunori Mizuno, Hans Peter Bächinger

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Promoting collagen synthesis: a viable strategy to combat skin ageing.Journal of enzyme inhibition and medicinal chemistry · 2025
    Review
  2. Around the collagen triple helix: an introduction to studying associated genetic and acquired diseases.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
  3. Collagen IV biosynthesis: Intracellular choreography of post-translational modifications.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
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  14. The Ehlers-Danlos syndromes.Nature reviews. Disease primers · 2020
    Review
  15. Article
  16. FKBP Ligands-Where We Are and Where to Go?Frontiers in pharmacology · 2018
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yoshihiro IshikawaFrom the Department of Biochemistry and Molecular Biology, Oregon Health & Science University and.
Kazunori MizunoResearch Department, Shriners Hospital for Children, Portland, Oregon 97239.
Hans Peter BächingerFrom the Department of Biochemistry and Molecular Biology, Oregon Health & Science University and hpb@shcc.org.
Shriners Hospitals for Children - Portland · USOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular matrix proteins are biosynthesized in the rough endoplasmic reticulum (rER), and the triple-helical protein collagen is the most abundant extracellular matrix component in the human body. Many enzymes, molecular chaperones, and post-translational modifiers facilitate collagen biosynthesis. Collagen contains a large number of proline residues, so the

Indexed as

Protein Processing, Post-TranslationalCollagen Type ICollagen Type IIICyclophilinsEndoplasmic ReticulumHumansHydroxyprolineProtein DomainsSubstrate SpecificityTacrolimus Binding ProteinsCollagen Type ICollagen Type IIIcyclophilin BCyclophilinsHydroxyprolineTacrolimus Binding Proteinsbiosynthesiscollagenendoplasmic reticulum (ER)molecular chaperonepost-translational modification (PM)prolyl isomerase

Identifiers

PMID28385890
PMCPMC5454108
OpenAlexW2604535029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.