Evidence map›Paper›PMID 28385881›Full record

ArticleAJNR. American journal of neuroradiology2017

Quantitative Measurement of CSF in Patients with Spontaneous Intracranial Hypotension.

H-C Chen, P-L Chen, Y-H Tsai, C-H Chen, C C-C Chen, J-W Chai

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

H-C ChenFrom the Departments of Radiology (H.-C.C., C.-H.C., C.C.-C.C., J.-W.C.).ORCID http://orcid.org/0000-0003-3544-5045
P-L ChenNeurology (P.-L.C.), Taichung Veterans General Hospital, Taichung, Taiwan.ORCID http://orcid.org/0000-0002-7254-0108
Y-H TsaiCollege of Medicine (Y.-H.T., J.-W.C.), China Medical University, Taichung, Taiwan.ORCID http://orcid.org/0000-0002-0215-9440
C-H ChenFrom the Departments of Radiology (H.-C.C., C.-H.C., C.C.-C.C., J.-W.C.).ORCID http://orcid.org/0000-0002-8856-4171
C C-C ChenFrom the Departments of Radiology (H.-C.C., C.-H.C., C.C.-C.C., J.-W.C.).ORCID http://orcid.org/0000-0002-3385-9466
J-W ChaiFrom the Departments of Radiology (H.-C.C., C.-H.C., C.C.-C.C., J.-W.C.) hubt@vghtc.gov.tw.ORCID http://orcid.org/0000-0002-2515-751X
3C Institute · USChina Medical University · TWNational Yang Ming Chiao Tung University · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCSF hypovolemia is a core feature of spontaneous intracranial hypotension. Spontaneous intracranial hypotension is characterized by orthostatic headache and radiologic manifestations, including CSF along the neural sleeves, diffuse pachymeningeal enhancement, and/or venous engorgement. However, these characteristics are only qualitative. Quantifying intraspinal CSF volumes could improve spontaneous intracranial hypotension diagnosis and evaluation of hypovolemic statuses in patients with spontaneous intracranial hypotension. The purpose of this study was to compare intraspinal CSF volumes across spontaneous intracranial hypotension stages and to test the clinical applicability of these measures. MATERIALS AND

methodsA cohort of 23 patients with spontaneous intracranial hypotension and 32 healthy controls was subjected to brain MR imaging and MR myelography with 1.5T imaging. An automatic threshold-based segmentation method was used to calculate intraspinal CSF volumes at initial hospitalization (spontaneous intracranial hypotension-initial), partial improvement (spontaneous intracranial hypotension-intermediate), and complete recovery (spontaneous intracranial hypotension-recovery) stages.

resultsThe mean intraspinal CSF volumes observed were the following: 95.31 mL for healthy controls, 72.31 mL for spontaneous intracranial hypotension-initial, 81.15 mL for spontaneous intracranial hypotension-intermediate, and 93.74 mL for spontaneous intracranial hypotension-recovery. Increased intraspinal CSF volumes were related to disease recovery (

conclusionsWith a threshold-based segmentation method, we found that spinal CSF hypovolemia is fundamentally related to spontaneous intracranial hypotension. Intraspinal CSF volumes could be a sensitive parameter for the evaluation of treatment response and follow-up monitoring in patients with spontaneous intracranial hypotension.

Indexed as

AdultFemaleHumansIntracranial HypotensionMagnetic Resonance ImagingMaleMyelography

Identifiers

PMID28385881
PMCPMC7960391
OpenAlexW2604951599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.