ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Epigenetic Age Acceleration Assessed with Human White-Matter Images.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- A systematic review of neuroimaging epigenetic research: calling for an increased focus on development.Molecular psychiatry · 2023Pooled it
- DNA methylation and brain structure and function across the life course: A systematic review.Neuroscience and biobehavioral reviews · 2020Pooled it
- A Systematic Review and Meta-analysis of Environmental, Lifestyle, and Health Factors Associated With DNA Methylation Age.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Pooled it
- Article
- Article
- Methylation and algorithms in biological aging: a scoping review.Frontiers in aging · 2025Review
- Racial Discrimination, Neural Connectivity, and Epigenetic Aging Among Black Women.JAMA network open · 2024Article
- Advanced biological ageing predicts future risk for neurological diagnoses and clinical examination findings.Brain : a journal of neurology · 2023Article
- Article
- Utility of DNA Methylation as a Biomarker in Aging and Alzheimer's Disease.Journal of Alzheimer's disease reports · 2023Review
- Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees.Epigenetics · 2022Article
- Association of Pediatric Buccal Epigenetic Age Acceleration With Adverse Neonatal Brain Growth and Neurodevelopmental Outcomes Among Children Born Very Preterm With a Neonatal Infection.JAMA network open · 2022Article
- Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume.GeroScience · 2022Article
- Aging biomarkers and the brain.Seminars in cell & developmental biology · 2021Review
- Association of Epigenetic Metrics of Biological Age With Cortical Thickness.JAMA network open · 2020Article
- Alteration of the brain methylation landscape following postnatal inflammatory injury in rat pups.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans.BMC medical genomics · 2019Article
- Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression.EBioMedicine · 2019Article
- DNA Methylation Age-Environmental Influences, Health Impacts, and Its Role in Environmental Epidemiology.Current environmental health reports · 2018Review
- Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents.AIDS (London, England) · 2018Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 1 country.
Funding
Abstract
The accurate estimation of age using methylation data has proved a useful and heritable biomarker, with acceleration in epigenetic age predicting a number of age-related phenotypes. Measures of white matter integrity in the brain are also heritable and highly sensitive to both normal and pathological aging processes across adulthood. We consider the phenotypic and genetic interrelationships between epigenetic age acceleration and white matter integrity in humans. Our goal was to investigate processes that underlie interindividual variability in age-related changes in the brain. Using blood taken from a Mexican-American extended pedigree sample (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.