Evidence map›Paper›PMID 28385815›Full record

ArticleBioscience reports2017

Effect of

Shabirul Haque, Gauri Patil, Abheepsa Mishra, Xiqian Lan, Waldemar Popik, Ashwani Malhotra, Karl Skorecki, Pravin C Singhal

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shabirul HaqueRenal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, U.S.A.
Gauri PatilRenal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, U.S.A.
Abheepsa MishraRenal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, U.S.A.
Xiqian LanRenal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, U.S.A.
Waldemar PopikCenter for Health Disparity Reseaerch, Meharry Medical College, Nashville, TN, U.S.A.
Ashwani MalhotraRenal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, U.S.A.
Karl SkoreckiNephrology and Molecular Medicine, Technion, Institute of Technology and Rambam Medical Center, Haifa, Israel.
Pravin C SinghalRenal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra North Shore LIJ Medical School, New York, U.S.A. psinghal@nshs.edu.
Technion – Israel Institute of Technology · IL

Funding

Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
p66ShcA in HIV associated NephropathyR01DK083931 · NIDDK · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SINGHAL, PRAVIN C · 2010 to 2013
$2.5M
Epigenetic factors and HIV-associated NephropathyR01DK098074 · NIDDK · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SINGHAL, PRAVIN C · 2013 to 2016
$2.5M
Renin Angioensin Aldosterone System in Drub Abuse and HIV-associated NephropathyR01DK084910 · NIDDK · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SINGHAL, PRAVIN C · 2010 to 2014
$1.7M
NIDDK NIH HHS R01 DK083931NIDDK NIH HHS R01 DK084910NIDDK NIH HHS R01 DK098074NIMHD NIH HHS G12 MD007586
6 · The paper itself

Abstract

Gene sequence mutations may alter mRNA transcription, transcript stability, protein translation, protein stability and protein folding. Apolipoprotein L1 (APOL1) has two sets of sequence variants that are risk factors for kidney disease development, APOL1G1 (substitution mutation) and APOL1G2 (deletion mutation). Our present study focuses on the impact of these variants on

Indexed as

Genetic VariationAmino Acid SubstitutionApolipoprotein L1Cell DifferentiationCell LineCell ProliferationEndoplasmic Reticulum Chaperone BiPGene DeletionGene Expression RegulationHeat-Shock ProteinsHEK293 CellsHumansKidney DiseasesPodocytesProtein BiosynthesisRNA, MessengerAPOL1 protein, humanApolipoprotein L1Endoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsHSPA5 protein, humanRNA, MessengerAPOL1APOL1 disease risk variantsAPOL1 gene product

Identifiers

PMID28385815
PMCPMC5408699
OpenAlexW2604140295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.