Evidence map›Paper›PMID 28385729›Full record

ArticlePlant physiology2017

Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis.

Adam Jozwiak, Agata Lipko, Magdalena Kania, Witold Danikiewicz, Liliana Surmacz, Agnieszka Witek, Jacek Wojcik, Konrad Zdanowski, Cezary Pączkowski, Tadeusz Chojnacki and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Plant physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Adam JozwiakInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).ORCID http://orcid.org/0000-0002-7666-7747
Agata LipkoInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).ORCID http://orcid.org/0000-0002-4054-610X
Magdalena KaniaInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).
Witold DanikiewiczInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).ORCID http://orcid.org/0000-0003-0484-2689
Liliana SurmaczInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).ORCID http://orcid.org/0000-0002-9517-1608
Agnieszka WitekInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).
Jacek WojcikInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).
Konrad ZdanowskiInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).
Cezary PączkowskiInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).
Tadeusz ChojnackiInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.).
Jaroslaw PoznanskiInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.); jarek@ibb.waw.pl ewas@ibb.waw.pl.
Ewa SwiezewskaInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland (A.J., A.L., L.S., A.W., J.W., K.Z., T.C., J.P., E.S.); jarek@ibb.waw.pl ewas@ibb.waw.pl.ORCID http://orcid.org/0000-0002-3439-8948
University of Siedlce · PLInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cooperation of the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, operating in parallel in plants to generate isoprenoid precursors, has been studied extensively. Elucidation of the isoprenoid metabolic pathways is indispensable for the rational design of plant and microbial systems for the production of industrially valuable terpenoids. Here, we describe a new method, based on numerical modeling of mass spectra of metabolically labeled dolichols (Dols), designed to quantitatively follow the cooperation of MVA and MEP reprogrammed upon osmotic stress (sorbitol treatment) in Arabidopsis (

Indexed as

Models, TheoreticalArabidopsisCarbon IsotopesChromatography, GasDolicholsErythritolIsotope LabelingMetabolic Networks and PathwaysMevalonic AcidOsmotic PressurePhytosterolsSorbitolSpectrometry, Mass, Electrospray IonizationSugar PhosphatesTerpenesXylulose1-deoxy-2-pentulose2-C-methylerythritol 4-phosphateCarbon IsotopesDolicholsErythritolMevalonic AcidmevalonolactonePhytosterolsSorbitolSugar PhosphatesTerpenesXylulose

Identifiers

PMID28385729
PMCPMC5462023
OpenAlexW2605266993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.