ReviewEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology2018
Thyroid cancer surgery guidelines in an era of de-escalation.
Review in European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Follow-up and transition of care for low recurrence risk thyroid cancer patients in Canada.European thyroid journal · 2025Guideline
- Health-related quality of life in cancer survivors 5 years after total thyroidectomy: a population-based study.Journal of the Endocrine Society · 2026Article
- Validation of the 2025 ATA risk stratification system in a cohort of patients with papillary thyroid carcinoma.The Journal of clinical endocrinology and metabolism · 2026Observational
- Preoperative and Intraoperative Assessment of Extrathyroidal Extension in Unilateral Papillary Thyroid Carcinoma: Does It Necessitate Total Thyroidectomy?Journal of surgical oncology · 2026Article
- De-escalation implementation in low-risk papillary thyroid cancer: a nationwide survey.Endocrine connections · 2026Article
- Review
- Surgical Optimization in Preoperatively Low-risk cN1a PTC: A Predictive Model for High-Volume Central Lymph Node Metastasis.Annals of surgical oncology · 2026Article
- Impact of surgical volume and specialist availability on thyroidectomy outcomes in Brazil: an ecological study with a nationwide retrospective analysis of 230,345 cases (2008-2023).Sao Paulo medical journal = Revista paulista de medicina · 2026Article
- Article
- Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation.World journal of clinical oncology · 2023Review
- Novel Strategies for Managing Retropharyngeal Lymph Node Metastases in Head and Neck and Thyroid Cancer with Transoral Robotic Surgery (TORS).Annals of surgical oncology · 2022Review
- Biodegradable iron oxide nanoparticles for intraoperative parathyroid gland imaging in thyroidectomy.PNAS nexus · 2022Article
- Thyroid stimulating hormone suppression and recurrence after thyroid lobectomy for papillary thyroid carcinoma.Endocrine · 2022Article
- Yield and costs of molecular diagnostics on thyroid cytology slides in the Netherlands, adapting the Bethesda classification.Endocrinology, diabetes & metabolism · 2021Article
- Decline in radioiodine use but not total thyroidectomy in thyroid cancer patients treated in the United Arab Emirates - A retrospective study.Annals of medicine and surgery (2012) · 2021Article
- Physician Confidence in Neck Ultrasonography for Surveillance of Differentiated Thyroid Cancer Recurrence.JAMA otolaryngology-- head & neck surgery · 2020Article
- Sternal metastatectomy in a case of papillary thyroid carcinoma.BMJ case reports · 2020Article
- The Identification of Intraoperative Risk Factors Can Reduce, but Not Exclude, the Need for Completion Thyroidectomy in Low-Risk Papillary Thyroid Cancer Patients.Thyroid : official journal of the American Thyroid Association · 2020Article
- Fine-Needle Aspiration of Subcentimeter Thyroid Nodules in the Real-World Management.Cancer management and research · 2020Article
- Explaining the Variation in Surgical Practice for Differentiated Thyroid Cancer in Ontario, Canada.JAMA otolaryngology-- head & neck surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Well-differentiated thyroid carcinoma has seen a tremendous rise in global incidence over the past three decades, largely owing to widespread screening and identification of small, incidentally detected tumors. With this increased incidence has emerged a movement questioning whether all cases of thyroid cancer merit a treatment approach focused on oncologic completeness. Such trends towards thoughtful, evidence-based treatment de-escalation paradigms reflect better risk stratification of thyroid cancers, and recognition that not all detected disease poses a threat to health or survival. Thus, national and professional guidelines are evolving to incorporate higher thresholds for surgery, acceptance of less than total thyroidectomy in specific circumstances, higher thresholds for adjuvant therapy, and introduction of the role of active surveillance for selected cases of low risk disease. Despite these common themes, there are significant differences among guidelines. This lack of consensus in guidelines persists due to variation in clinical practice patterns, differences in consideration and interpretation of existing evidence, cultural and geographical considerations, and resources available for both diagnosis and treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.