ArticleMolecular brain2017
Comparative analysis of A-to-I editing in human and non-human primate brains reveals conserved patterns and context-dependent regulation of RNA editing.
Article in Molecular brain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- SARS-CoV-2-induced dysregulation in ADAR editing patterns persists post viral clearance in individuals with mild COVID-19.Frontiers in cellular and infection microbiology · 2026Article
- Loss of CaProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Regulation and functional consequences of mGluRNA (New York, N.Y.) · 2021Article
- Pig-specific RNA editing during early embryo development revealed by genome-wide comparisons.FEBS open bio · 2020Article
- GABAFrontiers in systems neuroscience · 2019Article
- Experience-dependent neural plasticity, learning, and memory in the era of epitranscriptomics.Genes, brain, and behavior · 2018Review
- A-to-I RNA editing in the rat brain is age-dependent, region-specific and sensitive to environmental stress across generations.BMC genomics · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A-to-I RNA editing is an important process for generating molecular diversity in the brain through modification of transcripts encoding several proteins important for neuronal signaling. We investigated the relationships between the extent of editing at multiple substrate transcripts (5HT2C, MGLUR4, CADPS, GLUR2, GLUR4, and GABRA3) in brain tissue obtained from adult humans and rhesus macaques. Several patterns emerged from these studies revealing conservation of editing across primate species. Additionally, variability in the human population allows us to make novel inferences about the co-regulation of editing at different editing sites and even across different brain regions.
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Registered trials
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