ArticleJournal of intensive care medicine2018
Association of Household Income Level and In-Hospital Mortality in Patients With Sepsis: A Nationwide Retrospective Cohort Analysis.
Article in Journal of intensive care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities.International journal for equity in health · 2024Pooled it
- Association Between Community-Level Social Determinants of Health and Sepsis Incidence and Mortality: A Scoping Review.Critical care explorations · 2026Article
- The incidence and risk factors of sepsis following ovarian cancer surgery: A retrospective Nationwide Inpatient Sample database study.PloS one · 2026Article
- A Research Agenda to Mitigate Racial and Ethnic Disparities in U.S. Critical Care Medicine: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Associations Among Reduced Income, Unhealthy Habits, the Prevalence of Non-Communicable Diseases, and Multimorbidity in Middle-Aged and Older US Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Analysis of the impact of maternal sepsis on pregnancy outcomes: a population-based retrospective study.BMC pregnancy and childbirth · 2024Article
- The Global Burden of Sepsis and Septic Shock.Epidemiologia (Basel, Switzerland) · 2024Review
- Hospital-Onset Sepsis Warrants Expanded Investigation and Consideration as a Unique Clinical Entity.Chest · 2024Review
- Association of socioeconomic deprivation with outcomes in critically ill adult patients: an observational prospective multicenter cohort study.Annals of intensive care · 2024Article
- Lower socioeconomic status is not associated with severity of adolescent idiopathic scoliosis: a matched cohort analysis.Spine deformity · 2023Article
- Order Set Usage is Associated With Lower Hospital Mortality in Patients With Sepsis.Critical care explorations · 2023Article
- Epidemiologic Study of Intensive Care Unit Admission in South Korea: A Nationwide Population-Based Cohort Study from 2010 to 2019.International journal of environmental research and public health · 2022Article
- Home-to-hospital distance and outcomes among community-acquired sepsis hospitalizations.Annals of epidemiology · 2022Article
- Disparities Associated with Sepsis Mortality in Critically Ill Children.Journal of pediatric intensive care · 2022Article
- The impact of medical insurance reimbursement on postoperative inflammation reaction in distinct cardiac surgery from a single center.BMC health services research · 2022Article
- Association between sepsis incidence and regional socioeconomic deprivation and health care capacity in Germany - an ecological study.BMC public health · 2021Article
- Nationwide case-control study of risk factors and outcomes for community-acquired sepsis.Scientific reports · 2021Article
- Association of Hospitalised Infection With Socioeconomic Status in Patients With Rheumatoid Arthritis Receiving Biologics or Tofacitinib: A Population-Based Cohort Study.Frontiers in medicine · 2021Article
- Health Inequalities Among Elderly Type 2 Diabetes Mellitus Patients in Japan.Population health management · 2020Article
- Factors associated with sepsis risk in immune-mediated inflammatory diseases receiving tumor necrosis factor inhibitors: a nationwide study.Therapeutic advances in musculoskeletal disease · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveAssociations between low socioeconomic status (SES) and poor health outcomes have been demonstrated in a variety of conditions. However, the relationship in patients with sepsis is not well described. We investigated the association of lower household income with in-hospital mortality in patients with sepsis across the United States.
methodsRetrospective nationwide cohort analysis utilizing the Nationwide Inpatient Sample (NIS) from 2011. Patients aged 18 years or older with sepsis were included. Socioeconomic status was approximated by the median household income of the zip code in which the patient resided. Multivariate logistic modeling incorporating a validated illness severity score for sepsis in administrative data was performed.
resultsA total of 8 023 590 admissions from the 2011 NIS were examined. A total of 671 858 patients with sepsis were included in the analysis. The lowest income residents compared to the highest were younger (66.9 years, standard deviation [SD] = 16.5 vs 71.4 years, SD = 16.1, P < .01), more likely to be female (53.5% vs 51.9%, P < .01), less likely to be white (54.6% vs 76.6%, P < .01), as well as less likely to have health insurance coverage (92.8% vs 95.9%, P < .01). After controlling for severity of sepsis, residing in the lowest income quartile compared to the highest quartile was associated with a higher risk of mortality (odds ratio [OR]: 1.06, 95% confidence interval [CI]: 1.03-1.08, P < .01). There was no association seen between the second (OR: 1.02, 95% CI: 0.99-1.05, P = .14) and third (OR: 0.99, 95% CI: 0.97-1.01, P = .40) quartiles compared to the highest.
conclusionAfter adjustment for severity of illness, patients with sepsis who live in the lowest median income quartile had a higher risk of mortality compared to residents of the highest income quartile. The association between SES and mortality in sepsis warrants further investigation with more comprehensive measures of SES.
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