Evidence map›Paper›PMID 28385043›Full record

Trial reportResearch in sports medicine (Print)

The dose-response effects of aerobic exercise on musculoskeletal injury: a post hoc analysis of a randomized trial.

Justin C Brown, Kathryn H Schmitz

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Research in sports medicine (Print). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. The Association Between Fitness Test Scores and Musculoskeletal Injury in Police Officers.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Justin C Browna Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine , University of Pennsylvania , PA , United States of America.
Kathryn H Schmitza Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine , University of Pennsylvania , PA , United States of America.

Funding

The Women In Steady Exercise Research (WISER) SurwVor TrialU54CA155850 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SCHMITZ, KATHRYN H. · 2011 to 2015
$9.1M
WISER SisterR01CA131333 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SCHMITZ, KATHRYN H. · 2008 to 2012
$3.2M
The COURAGE Trial: Colon Recurrence and Aerobic Exercise: A Feasibility StudyR21CA182767 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SCHMITZ, KATHRYN H. · 2014 to 2015
$377k
Effects of Exercise on Visceral Adiposity & Hyperinsulinemia in Colon Cancer SurvivorF31CA192560 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BROWN, JUSTIN C · 2015 to 2016
$69k
NCI NIH HHS F31 CA192560NCI NIH HHS R01 CA131333NCI NIH HHS R21 CA182767NCI NIH HHS U54 CA155850
6 · The paper itself

Abstract

In a post hoc analysis, we quantified the risk of musculoskeletal injury (MSI) associated with different volumes of aerobic exercise in a randomized trial. Premenopausal women (n = 119) were randomized to one of three groups: low-dose aerobic exercise (150 min·per week), high-dose aerobic exercise (300 min·per week) or control (usual activity) for 5 months. Compared to the control group, the risk of reporting an acute MSI increased with higher volumes of aerobic exercise, with a similar pattern observed for recurrent MSI. The risk of reporting an MSI severe enough to impair activities of daily living did not increase with higher volumes of aerobic exercise. Approximately half of MSI were causally attributed to aerobic exercise. The risk of experiencing an acute or recurrent MSI increases with higher volumes of aerobic exercise; however, the risk of experiencing an MSI severe enough to impair activities of daily living does not increase with higher volumes of aerobic exercise.

Indexed as

ExerciseExercise TherapyActivities of Daily LivingAdultAthletic InjuriesFemaleHumansMusculoskeletal SystemPremenopauseRisk Factorsadverse eventimpairmentJointphysical activitysoft-tissue

Identifiers

PMID28385043
PMCPMC5549269

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.