Evidence map›Paper›PMID 28384311›Full record

ArticlePloS one2017

Comparison of two prognostic scores (BSI and FACED) in a Spanish cohort of adult patients with bronchiectasis and improvement of the FACED predictive capacity for exacerbations.

Edmundo Rosales-Mayor, Eva Polverino, Laura Raguer, Victoria Alcaraz, Albert Gabarrus, Otavio Ranzani, Rosario Menendez, Antoni Torres

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. A systematic literature review of the clinical and socioeconomic burden of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Edmundo Rosales-MayorFundació Clínic, IDIBAPS, CIBERES, Servicio de Neumología, Hospital Clinic de Barcelona, Barcelona, España.
Eva PolverinoFundació Clínic, IDIBAPS, CIBERES, Servicio de Neumología, Hospital Clinic de Barcelona, Barcelona, España.
Laura RaguerFacultad de Medicina, Universidad de Barcelona, Barcelona, España.
Victoria AlcarazFundació Clínic, IDIBAPS, CIBERES, Servicio de Neumología, Hospital Clinic de Barcelona, Barcelona, España.
Albert GabarrusFundació Clínic, IDIBAPS, CIBERES, Servicio de Neumología, Hospital Clinic de Barcelona, Barcelona, España.
Otavio RanzaniFundació Clínic, IDIBAPS, CIBERES, Servicio de Neumología, Hospital Clinic de Barcelona, Barcelona, España.
Rosario MenendezCIBERES, Instituto de Investigación Sanitaria La Fe, Servicio de Neumología, Hospital Universitario y Politécnico La Fe de Valencia, Valencia, España.
Antoni TorresFundació Clínic, IDIBAPS, CIBERES, Servicio de Neumología, Hospital Clinic de Barcelona, Barcelona, España.ORCID http://orcid.org/0000-0002-5649-7699
Hospital Clínic de Barcelona · ESCentro de Investigación Biomédica en Red · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiectasis (BE) is a chronic and heterogeneous respiratory disease that requires a multidimensional scoring system to properly assess severity. The aim of this study was to compare the severity stratification by 2 validated scores (BSI and FACED) in a BE cohort and to determine their predictive capacity for exacerbations and hospitalizations. Moreover, we proposed a modified version of FACED which was created to better predict the risk of exacerbations in clinical practice. We performed a prospective cohort study including BE patients >18 years old with a follow-up period of 1-year. One-hundred eighty-two patients (40% males; mean age 68) were studied. Patients were stratified according to the number of exacerbations during the follow-up, and according to BSI and FACED scores. BSI classified most of our patients as severe 99 (54.4%) or moderate 47 (25.8%), while FACED mainly classified as mild 108 (59.3%) or moderate 61 (33.5%). BSI and FACED showed an area under ROC curve (AUC) for exacerbations of 0.808 and 0.734; and for hospitalizations (due to BE exacerbations) of 0.893 and 0.809, respectively. Subsequently, we modified FACED by adding previous exacerbations (Exa-FACED) and this new score classified patients as mild 48.4%, moderate 34.6% and severe 17.0%, with an improved AUC for exacerbations (0.760) and hospitalizations (0.820). Despite previous validations of BSI and FACED, they classified our patients very differently. As expected, FACED showed poor prognostic capacity for exacerbations. We support the Exa-FACED score to predict the risk future exacerbations for been easy to use in clinical practice.

Indexed as

AgedBronchiectasisCohort StudiesFemaleHumansMaleMiddle AgedPrognosisSpain

Identifiers

PMID28384311
PMCPMC5383257
OpenAlexW2604690501

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.