Observational studyMedicine2017
Poststroke alterations in heart rate variability during orthostatic challenge.
Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- The Aphasia Physical EXercise (APEX) study: feasibility of a new high-intensity functional interval training for stroke survivors with aphasia.Aphasiology · 2026Article
- Higher Heart Rates During Locomotor High-Intensity Interval Training Are Associated With Gait Asymmetry and Fatigue After Stroke.Cardiopulmonary physical therapy journal · 2025Article
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- Article
- Very early tilt-table verticalization unmasks impaired cerebral autoregulation within 24 h after endovascular thrombectomy: a transcranial Doppler study.Frontiers in neurology · 2025Article
- Clinical approaches for poststroke seizure: a review.Frontiers in neurology · 2024Review
- Elevated biomarkers of neural injury in older adults following head-down bed rest: links to cardio-postural deconditioning with spaceflight and aging.Frontiers in human neuroscience · 2023Article
- Effects of focus training on heart rate variability in post-stroke fatigue patients.Journal of translational medicine · 2022Article
- Canadian aging and inactivity study: Spaceflight-inspired exercises during head-down tilt bedrest blunted reductions in muscle-pump but not cardiac baroreflex in older persons.Frontiers in physiology · 2022Article
- Diagnosing Neurally Mediated Syncope Using Classification Techniques.Journal of clinical medicine · 2021Article
- Support Vector Machine-Based Classification of Vasovagal Syncope Using Head-Up Tilt Test.Biology · 2021Article
- The Impact of Cardiovascular Rehabilitation on Psychophysiological Stress, Personality and Tryptophan Metabolism: A Randomized Pilot Feasibility Study.Antioxidants (Basel, Switzerland) · 2021Article
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- Cardiac Autonomic Response to Active Standing in Calcific Aortic Valve Stenosis.Journal of clinical medicine · 2021Article
- Validity of the Polar V800 Monitor for Assessing Heart Rate Variability in Elderly Adults under Mental Stress and Dual Task Conditions.International journal of environmental research and public health · 2021Article
- Postural Changes on Heart Rate Variability among Older Population: A Preliminary Study.Current gerontology and geriatrics research · 2021Article
- Cardio-postural interactions and muscle-pump baroreflex are severely impacted by 60-day bedrest immobilization.Scientific reports · 2020Article
- Falls Risk, Circadian Rhythms and Melatonin: Current Perspectives.Clinical interventions in aging · 2020Review
- Assessment of Ultra-Short Heart Variability Indices Derived by Smartphone Accelerometers for Stress Detection.Sensors (Basel, Switzerland) · 2019Article
- Relationship between Ischemic Stroke and Pulse Rate Variability as a Surrogate of Heart Rate Variability.Brain sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Older adults following recovery from ischemic stroke have a higher incidence of orthostatic hypotension, syncope, and fall risk, which may be related to impaired autonomic responses limiting the ability to maintain cerebral blood flow. Thus, we investigated cerebrovascular and cardiovascular regulation in 23 adults ≥55 years of age, 10 diagnosed with ischemic stroke, and 13 age-matched healthy controls when sitting at rest and upon standing to compare differences of autonomic variables at ∼7 months (218 ± 41 days) poststroke.Arterial blood pressure via finger plethysmography, muscle-pump baroreflex via electromyography, heart rate variability via 3-lead ECG, and cerebral blood flow velocity via transcranial Doppler were analyzed while sitting for 5 minutes and then during quiet standing for 5 minutes.From the seated to standing position, the stroke group had significantly greater decline in the low frequency component of heart rate variability (164 [79] vs 25 [162] ms; P = 0.043). All other cardiovascular parameters and assessments of autonomic function were not significantly different between the two groups.Our findings support the hypothesis of continued autonomic dysfunction after recovery from ischemic stroke, with potential attenuation of the cardiovascular response to standing. However, further investigation is required to determine the mechanisms underlying the increased risk of orthostatic hypotension, syncope, and falls poststroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.