Evidence map›Paper›PMID 28382883›Full record

Trial reportPsychological medicine2017

Adjunctive yoga v. health education for persistent major depression: a randomized controlled trial.

L A Uebelacker, G Tremont, L T Gillette, G Epstein-Lubow, D R Strong, A M Abrantes, A R Tyrka, T Tran, B A Gaudiano, I W Miller

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 6 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 6 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

L A UebelackerButler Hospital,Providence, RI,USA.
G TremontAlpert Medical School of Brown University,Providence, RI,USA.
L T GilletteEyes of the World Yoga Center,North Kingstown, RI,USA.
G Epstein-LubowButler Hospital,Providence, RI,USA.
D R StrongUniversity of California,San Diego, CA,USA.
A M AbrantesButler Hospital,Providence, RI,USA.
A R TyrkaButler Hospital,Providence, RI,USA.
T TranAlpert Medical School of Brown University,Providence, RI,USA.
B A GaudianoButler Hospital,Providence, RI,USA.
I W MillerButler Hospital,Providence, RI,USA.
Providence College · USBrown University · USRhode Island Hospital · USButler Hospital · USUniversity of California, San Diego · US

Funding

RCT of hatha yoga for persistent depressionR01NR012005 · NINR · BUTLER HOSPITAL (PROVIDENCE, RI) · PI UEBELACKER, LISA A · 2011 to 2014
$1.6M
NINR NIH HHS R01 NR012005
6 · The paper itself

Abstract

backgroundThe objective of this study was to determine whether hatha yoga is an efficacious adjunctive intervention for individuals with continued depressive symptoms despite antidepressant treatment.

methodWe conducted a randomized controlled trial of weekly yoga classes (n = 63) v. health education classes (Healthy Living Workshop; HLW; n = 59) in individuals with elevated depression symptoms and antidepressant medication use. HLW served as an attention-control group. The intervention period was 10 weeks, with follow-up assessments 3 and 6 months afterwards. The primary outcome was depression symptom severity assessed by blind rater at 10 weeks. Secondary outcomes included depression symptoms over the entire intervention and follow-up periods, social and role functioning, general health perceptions, pain, and physical functioning.

resultsAt 10 weeks, we did not find a statistically significant difference between groups in depression symptoms (b = -0.82, s.e. = 0.88, p = 0.36). However, over the entire intervention and follow-up period, when controlling for baseline, yoga participants showed lower levels of depression than HLW participants (b = -1.38, s.e. = 0.57, p = 0.02). At 6-month follow-up, 51% of yoga participants demonstrated a response (⩾50% reduction in depression symptoms) compared with 31% of HLW participants (odds ratio = 2.31; p = 0.04). Yoga participants showed significantly better social and role functioning and general health perceptions over time.

conclusionsAlthough we did not see a difference in depression symptoms at the end of the intervention period, yoga participants showed fewer depression symptoms over the entire follow-up period. Benefits of yoga may accumulate over time.

Indexed as

Outcome Assessment, Health CareYogaAdultAntidepressive AgentsCombined Modality TherapyFemaleFollow-Up StudiesHealth EducationHumansMajor Depressive DisorderMaleMiddle AgedAntidepressive AgentsHatha yogamajor depression

Identifiers

PMID28382883
PMCPMC5548599
OpenAlexW2604987397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.