Evidence map›Paper›PMID 28382737›Full record

ArticleAmerican journal of reproductive immunology (New York, N.Y. : 1989)2017

Leukocyte counts and lymphocyte subsets in relation to pregnancy and HIV infection in Malawian women.

Wilson L Mandala, Esther N Gondwe, Malcolm E Molyneux, Jenny M MacLennan, Calman A MacLennan

Open access · hybridAbstract read
In one paragraph

Article in American journal of reproductive immunology (New York, N.Y. : 1989), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
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  8. Leukocyte counts and lymphocyte subsets in relation to pregnancy and HIV infection in Malawian women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Wilson L MandalaMalawi-Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi.ORCID http://orcid.org/0000-0001-9386-9239
Esther N GondweMalawi-Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi.
Malcolm E MolyneuxMalawi-Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi.
Jenny M MacLennanMalawi-Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi.
Calman A MacLennanMalawi-Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi.
University of Liverpool · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

problemWe investigated leukocyte and lymphocyte subsets in HIV-infected or HIV-uninfected, pregnant or non-pregnant Malawian women to explore whether HIV infection and pregnancy may act synergistically to impair cellular immunity. METHOD OF STUDY: We recruited 54 pregnant and 48 non-pregnant HIV-uninfected women and 24 pregnant and 20 non-pregnant HIV-infected Malawian women. We compared peripheral blood leukocyte and lymphocyte subsets between women in the four groups.

resultsParturient HIV-infected and HIV-uninfected women had more neutrophils (each P<.0001), but fewer lymphocytes (P<.0001; P=.0014) than non-pregnant women. Both groups had fewer total T cells (P<.0001; P=.002) and CD8

conclusionMalawian women at parturition have an increased total white cell count due to neutrophilia and an HIV-unrelated pan-lymphopenia.

Indexed as

Immunity, CellularPregnancyAdolescentAdultAgedFemaleHIVHIV InfectionsHumansImmunophenotypingLymphocyte CountLymphocyte SubsetsMalawiMiddle AgedParturitionPregnancy ComplicationsReceptors, Antigen, T-Cell, gamma-deltaHIVleukocyteslymphocytesparturitionpregnancysepsis

Identifiers

PMID28382737
PMCPMC5573949
OpenAlexW2605048558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.