Evidence map›Paper›PMID 28382721›Full record

ArticleMolecular oral microbiology2017

The two-component system VicRK regulates functions associated with Streptococcus mutans resistance to complement immunity.

Livia A Alves, Erika N Harth-Chu, Thais H Palma, Rafael N Stipp, Flávia S Mariano, José F Höfling, Jacqueline Abranches, Renata O Mattos-Graner

Abstract read
In one paragraph

Article in Molecular oral microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. PepO and CppA modulateVirulence · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Virulence · 2020
    Article
  11. Article
  12. Article
  13. Novel Probiotic Mechanisms of the Oral BacteriumApplied and environmental microbiology · 2019
    Article
  14. Article
  15. PcsB Expression Diversity Influences onFrontiers in microbiology · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Relative stability ofJournal of oral biology and craniofacial research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Livia A AlvesDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.
Erika N Harth-ChuDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.
Thais H PalmaDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.
Rafael N StippDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.
Flávia S MarianoDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.
José F HöflingDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.
Jacqueline AbranchesDepartment of Oral Biology, College of Dentistry - University of Florida, Gainesville, FL, USA.
Renata O Mattos-GranerDepartment of Oral Diagnosis, Piracicaba Dental School - State University of Campinas, Piracicaba, SP, Brazil.ORCID 0000-0001-8309-8135
Universidade Estadual de Campinas (UNICAMP) · BRUniversity of Florida · US

Funding

Intracellular Invasion by Streptococcus mutans: Significance in DiseaseR01DE022559 · NIDCR · UNIVERSITY OF ROCHESTER · PI Jacqueline Abranches, Christine M. Szymanski · 2013 to 2026
$4.8M
NIDCR NIH HHS R01 DE022559
6 · The paper itself

Abstract

Streptococcus mutans, a dental caries pathogen, can promote systemic infections upon reaching the bloodstream. The two-component system (TCS) VicRK

Indexed as

Gene Expression Regulation, BacterialImmune EvasionBacteremiaBacterial ProteinsBiofilmsComplement C3bDental CariesGene ExpressionHumansImmunoglobulin GMembrane ProteinsMutationProtein BindingStreptococcus mutansSucroseVirulenceBacterial ProteinsComplement C3bImmunoglobulin GMembrane ProteinsSucroseYycF protein, Bacteriabacteremiacomplement systemStreptococcus mutanstwo-component system

Identifiers

PMID28382721
PMCPMC5585069
OpenAlexW2605310179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.