ArticleMagma (New York, N.Y.)2017
Measurement of vertebral bone marrow proton density fat fraction in children using quantitative water-fat MRI.
Article in Magma (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- The quantitative parameters derived from IDEAL-IQ in the lumbar vertebrae of healthy children: a pilot study of bone development.Quantitative imaging in medicine and surgery · 2024Article
- Associations between vertebral bone marrow fat and sagittal spine alignment as assessed by chemical shift-encoding-based water-fat MRI.Journal of orthopaedic surgery and research · 2023Article
- Assessing breast density using the chemical-shift encoding-based proton density fat fraction in 3-T MRI.European radiology · 2023Article
- Diffuse reflectance spectroscopy of the spine: improved breach detection with angulated fibers.Biomedical optics express · 2023Article
- 3T-MRI-based age, sex and site-specific markers of musculoskeletal health in healthy children and young adults.Endocrine connections · 2022Article
- The Implications of Bone Marrow Adipose Tissue on Inflammaging.Frontiers in endocrinology · 2022Review
- Bone marrow adipose tissue content in Latino adolescents with prediabetes and obesity.Obesity (Silver Spring, Md.) · 2021Article
- The Effect of Roux-en-Y Gastric Bypass on Bone Marrow Adipose Tissue and Bone Mineral Density in Postmenopausal, Nondiabetic Women.Obesity (Silver Spring, Md.) · 2021Article
- Survey of MRI Usefulness for the Clinical Assessment of Bone Microstructure.International journal of molecular sciences · 2021Review
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- Age- and BMI-related variations of fat distribution in sacral and lumbar bone marrow and their association with local muscle fat content.Scientific reports · 2020Article
- Analysis of muscle, hip, and subcutaneous fat in osteoporosis patients with varying degrees of fracture risk using 3T Chemical Shift Encoded MRI.Bone reports · 2020Article
- MRI Assessment of Bone Marrow Composition in Osteoporosis.Current osteoporosis reports · 2020Review
- Regional variation in paraspinal muscle composition using chemical shift encoding-based water-fat MRI.Quantitative imaging in medicine and surgery · 2020Article
- Vertebral Bone Marrow Heterogeneity Using Texture Analysis of Chemical Shift Encoding-Based MRI: Variations in Age, Sex, and Anatomical Location.Frontiers in endocrinology · 2020Article
- Association of thigh and paraspinal muscle composition in young adults using chemical shift encoding-based water-fat MRI.Quantitative imaging in medicine and surgery · 2020Article
- Reporting Guidelines, Review of Methodological Standards, and Challenges Toward Harmonization in Bone Marrow Adiposity Research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society.Frontiers in endocrinology · 2020Review
- Proximal femur fat fraction variation in healthy subjects using chemical shift-encoding based MRI.Scientific reports · 2019Article
- Marrow adipose tissue gradient is preserved through high protein diet and bed rest. A randomized crossover study.Bone reports · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo investigate the feasibility of employing a 3D time-interleaved multi-echo gradient-echo (TIMGRE) sequence to measure the proton density fat fraction (PDFF) in the vertebral bone marrow (VBM) of children and to examine cross-sectional changes with age and intra-individual variations from the lumbar to the cervical region in the first two decades of life. MATERIALS AND
methodsQuantitative water-fat imaging of the spine was performed in 93 patients (49 girls; 44 boys; age median 4.5 years; range 0.1-17.6 years). For data acquisition, a six-echo 3D TIMGRE sequence was used with phase correction and complex-based water-fat separation. Additionally, single-voxel MR spectroscopy (MRS) was performed in the L4 vertebrae of 37 patients. VBM was manually segmented in the midsagittal slice of each vertebra. Univariable and multivariable linear regression models were calculated between averaged lumbar, thoracic and cervical bone marrow PDFF and age with adjustments for sex, height, weight, and body mass index percentile.
resultsMeasured VBM PDFF correlated strongly between imaging and MRS (R
conclusionVBM development in children showed a sex-independent cross-sectional increase of PDFF correlating with the natural logarithm of age and an intra-individual decrease of PDFF from the lumbar to the cervical region in all age groups. The present results demonstrate the feasibility of using a 3D TIMGRE sequence for PDFF assessment in VBM of children.
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