Evidence map›Paper›PMID 28382425›Full record

ReviewClinical research in cardiology : official journal of the German Cardiac Society2017

Characteristics of PR interval as predictor for atrial fibrillation: association with biomarkers and outcomes.

Katja Schumacher, Nikolaos Dagres, Gerhard Hindricks, Daniela Husser, Andreas Bollmann, Jelena Kornej

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Atrial Cardiomyopathy: From Diagnosis to Treatment.Reviews in cardiovascular medicine · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Electrocardiographic parameters and the risk of new-onset atrial fibrillation in the general population: the Rotterdam Study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Electrocardiogram findings at the initiation of hemodialysis and types of subsequent cardiovascular events.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. The Dose-Dependent Effects of Spironolactone on TGF-Cardiology research and practice · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Katja SchumacherDepartment of Electrophysiology, Heart Center, HELIOS Kliniken GmbH, University of Leipzig, Struempellstrasse 39, 04289, Leipzig, Germany.
Nikolaos DagresDepartment of Electrophysiology, Heart Center, HELIOS Kliniken GmbH, University of Leipzig, Struempellstrasse 39, 04289, Leipzig, Germany.
Gerhard HindricksDepartment of Electrophysiology, Heart Center, HELIOS Kliniken GmbH, University of Leipzig, Struempellstrasse 39, 04289, Leipzig, Germany.
Daniela HusserDepartment of Electrophysiology, Heart Center, HELIOS Kliniken GmbH, University of Leipzig, Struempellstrasse 39, 04289, Leipzig, Germany.
Andreas BollmannDepartment of Electrophysiology, Heart Center, HELIOS Kliniken GmbH, University of Leipzig, Struempellstrasse 39, 04289, Leipzig, Germany.
Jelena KornejDepartment of Electrophysiology, Heart Center, HELIOS Kliniken GmbH, University of Leipzig, Struempellstrasse 39, 04289, Leipzig, Germany. jelena.kornej@gmx.de.ORCID http://orcid.org/0000-0003-3551-1145
Helios Kliniken · DELeipzig Heart Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PR interval may be considered as a simple and easily obtainable predictor for adverse events, including atrial fibrillation (AF), pacemaker implantation, and mortality. Interestingly, both high and low extremes of the PR duration are associated with AF risk. However, the results regarding PR prolongation as a risk factor for AF are inconsistent. Some studies have analyzed the impact of P duration (as a part of the PR interval) and demonstrated that the P-duration contributes to the length of PR interval and adverse outcomes. The PR prolongation could be considered as a marker for cardiovascular degenerative aging caused by myocardial fibrosis and vascular inflammation. Furthermore, due to PR prolongation chronically raised intra-atrial pressure and consequential neuro-hormonal activation predispose systemic vascular endothelial dysfunction and explain the associations with adverse vascular events. In this review, we discuss the association between biomarkers with PR interval in AF.

Indexed as

Atrial FibrillationRisk AssessmentElectrocardiographyGlobal HealthHeart RateHumansMorbidityRisk FactorsSeverity of Illness IndexSurvival RateAF incidenceAtrial fibrillationBiomarkersPR prolongationP wave morphology

Identifiers

PMID28382425
OpenAlexW2604640087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.