Evidence map›Paper›PMID 28382194›Full record

ArticleInternational journal of preventive medicine2017

Wound Healing Activity of Extracts and Formulations of

Samira Negahdari, Hamid Galehdari, Mahnaz Kesmati, Anahita Rezaie, Gholamreza Shariati

Open access · goldAbstract read
In one paragraph

Article in International journal of preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Pooled it
  2. Hormesis: induction byOpen medicine (Warsaw, Poland) · 2026
    Review
  3. Article
  4. Wound healing and photodynamic potential ofFrontiers in pharmacology · 2025
    Article
  5. Article
  6. Gels (Basel, Switzerland) · 2023
    Review
  7. Role of Herbal Extracts of Catechu fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  8. The Antioxidant and In Vitro Wound Healing Activity ofInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Chemical Composition ofPharmaceuticals (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
  13. Chemical Composition ofPlants (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. The Unexplored Wound Healing Activity ofMolecules (Basel, Switzerland) · 2021
    Article
  17. Review
  18. Wound healing Activities of the bioactive compounds fromSaudi journal of biological sciences · 2020
    Article
  19. Article
  20. Pharmacological Update Properties ofMolecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samira NegahdariDepartment of Genetics, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Hamid GalehdariDepartment of Genetics, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Mahnaz KesmatiDepartment of Biology, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Anahita RezaieDepartment of Veterinary, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Gholamreza ShariatiDepartment of Medical Genetics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Shahid Chamran University of Ahvaz · IRAhvaz Jundishapur University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong the most important factors in wound healing pathways are transforming growth factor beta1 and vascular endothelial growth factor. Fibroblasts are the main cell in all phases wound closure. In this study, the extracts of plant materials such as

methodsCytotoxic effects of each extract and their mixture were assessed on mouse skin fibroblasts cells using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. We performed migration assays to assess migration properties of mouse skin fibroblasts cells in response to the extracts. Changes in the gene expression of the

results

conclusionsThe present study demonstrated that the mentioned herbal extracts might be effective in wound healing, through the improvement in the migration of fibroblast cells and regulating the gene expression of

Indexed as

Fibroblastherbaltransforming growth factor-β1vascular endothelial growth factorwound healing

Identifiers

PMID28382194
PMCPMC5364744
OpenAlexW2594039483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.