Evidence map›Paper›PMID 28382172›Full record

ReviewTheranostics2017

Theranostic DNAzymes.

Wenhu Zhou, Jinsong Ding, Juewen Liu

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 242 citations in OpenAlex.

  1. Article
  2. DNA Flap-Mediated Control of Transcription for Programmable RNA Synthesis.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. DNA Catalysis: Design, Function, and Optimization.Molecules (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Article
  12. Surface engineeringExploration (Beijing, China) · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. CRISPR-based nucleic acid diagnostics for pathogens.Trends in analytical chemistry : TRAC · 2023
    Review
  17. Construction and Application of DNAzyme-based Nanodevices.Chemical research in Chinese universities · 2023
    Review
  18. Article
  19. Signal-on fluorescent sensing strategy for PbAnalytical and bioanalytical chemistry · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Wenhu ZhouXiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China, 410013.; Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada, N2L 3G1.
Jinsong DingXiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China, 410013.
Juewen LiuXiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China, 410013.; Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada, N2L 3G1.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNAzymes are catalytically active DNA molecules that are obtained via in vitro selection. RNA-cleaving DNAzymes have attracted significant attention for both therapeutic and diagnostic applications due to their excellent programmability, stability, and activity. They can be designed to cleave a specific mRNA to down-regulate gene expression. At the same time, DNAzymes can sense a broad range of analytes. By combining these two functions, theranostic DNAzymes are obtained. This review summarizes the progress of DNAzyme for theranostic applications. First,

Indexed as

AnimalsBiological TherapyBiomedical ResearchDiagnostic Tests, RoutineDNA, CatalyticHumansRNATheranostic NanomedicineDNA, CatalyticRNAbiosensorsdelivery.DNAzymesmetal ionsRNA

Identifiers

PMID28382172
PMCPMC5381262
OpenAlexW4232144512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.