Evidence map›Paper›PMID 28382048›Full record

ArticleFrontiers in plant science2017

Phylogeny Predicts the Quantity of Antimalarial Alkaloids within the Iconic Yellow

Carla Maldonado, Christopher J Barnes, Claus Cornett, Else Holmfred, Steen H Hansen, Claes Persson, Alexandre Antonelli, Nina Rønsted

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
11.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. A Review of Phytochemical and Pharmacological Studies onMolecules (Basel, Switzerland) · 2025
    Review
  6. Changes ofRoyal Society open science · 2023
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  7. Article
  8. Review
  9. Review
  10. Treatment of Erythroid Precursor Cells from β-Thalassemia Patients withInternational journal of molecular sciences · 2021
    Article
  11. Review
  12. Review
  13. Effect of Medium pH and Light on Quinidine Production inTurkish journal of pharmaceutical sciences · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Carla MaldonadoNatural History Museum of Denmark, University of CopenhagenCopenhagen, Denmark; Herbario Nacional de Bolivia, Universidad Mayor de San AndresLa Paz, Bolivia.
Christopher J BarnesNatural History Museum of Denmark, University of Copenhagen Copenhagen, Denmark.
Claus CornettAnalytical Biosciences, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen Copenhagen, Denmark.
Else HolmfredAnalytical Biosciences, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen Copenhagen, Denmark.
Steen H HansenAnalytical Biosciences, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen Copenhagen, Denmark.
Claes PerssonDepartment of Biological and Environmental Sciences, University of GothenburgGothenburg, Sweden; Gothenburg Global Biodiversity CentreGothenburg, Sweden.
Alexandre AntonelliDepartment of Biological and Environmental Sciences, University of GothenburgGothenburg, Sweden; Gothenburg Botanical GardenGothenburg, Sweden.
Nina RønstedNatural History Museum of Denmark, University of Copenhagen Copenhagen, Denmark.
University of Copenhagen · DKUniversity of Gothenburg · SEHigher University of San Andrés · BONatural History Museum Aarhus · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considerable inter- and intraspecific variation with respect to the quantity and composition of plant natural products exists. The processes that drive this variation remain largely unknown. Understanding which factors determine chemical diversity has the potential to shed light on plant defenses against herbivores and diseases and accelerate drug discovery. For centuries,

Indexed as

alkaloidsBoliviaCinchona calisayaclimatephylogenyplant chemical defenseplant–climate interactionsquinine

Identifiers

PMID28382048
PMCPMC5360753
OpenAlexW2603834948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.