Evidence map›Paper›PMID 28381457›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2017

A novel biomarker associated with distress in humans: calcium-binding protein, spermatid-specific 1 (CABS1).

Thomas Ritz, David Rosenfield, Chris D St Laurent, Ana F Trueba, Chelsey A Werchan, Pia D Vogel, Richard J Auchus, Eduardo Reyes-Serratos, A Dean Befus

Registry-linked trialAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03831750 (Assessing the Effectiveness of a Stress Reduction Intervention in Inflammatory Bowel Disease), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03831750 nacompletednot on this mapstarted 2019, after this paper: background citation

Assessing the Effectiveness of a Stress Reduction Intervention in Inflammatory Bowel Disease (IBD): a Prospective Randomized Controlled Trial (RCT)

TypeinterventionalSponsorUniversity of AlbertaRan2019 to 2021Enrolled101ConditionsInflammatory Bowel Diseases, Remission, Perceived StressArmsStress Reduction Intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas RitzDepartment of Psychology, Southern Methodist University, Dallas, Texas.
David RosenfieldDepartment of Psychology, Southern Methodist University, Dallas, Texas.
Chris D St LaurentPulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Ana F TruebaDepartment of Psychology, Southern Methodist University, Dallas, Texas.
Chelsey A WerchanDepartment of Psychology, Southern Methodist University, Dallas, Texas.
Pia D VogelDepartment of Biological Sciences, Southern Methodist University, Dallas, Texas; and.
Richard J AuchusDepartment of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan.
Eduardo Reyes-SerratosPulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
A Dean BefusPulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; dean.befus@ualberta.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium-binding protein spermatid-specific 1 (CABS1) is expressed in the human submandibular gland and has an anti-inflammatory motif similar to that in submandibular rat 1 in rats. Here, we investigate CABS1 in human saliva and its association with psychological and physiological distress and inflammation in humans. Volunteers participated across three studies:

Indexed as

AdolescentAdultAffectAsthmaBiomarkersCalcium-Binding ProteinsFemaleForced Expiratory VolumeHeart RateHumansHydrocortisoneLeukotriene B4MaleMathematical ConceptsMiddle AgedMolecular WeightBiomarkersCABS1 protein, humanCalcium-Binding ProteinsHydrocortisoneLeukotriene B4Vascular Endothelial Growth Factor AVEGFA protein, humanacute and chronic stressanti-inflammatory activitycalcium-binding protein spermatid-specific 1cortisolnegative affectsalivasubmandibular rat 1

Identifiers

PMID28381457
PMCPMC5495925

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.