Evidence map›Paper›PMID 28380669›Full record

ArticleJournal of biomedical materials research. Part A2017

Antibacterial and bioactive coatings on titanium implant surfaces.

Anupama Kulkarni Aranya, Smruti Pushalkar, Minglei Zhao, Racquel Z LeGeros, Yu Zhang, Deepak Saxena

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.

  1. Microbial Biofilm Decontamination on Dental Implant Surfaces: A Mini Review.Frontiers in cellular and infection microbiology · 2021
    Pooled it
  2. Review
  3. Article
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  7. Article
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  12. Review
  13. Biomimetic Coatings in Implant Dentistry: A Quick Update.Journal of functional biomaterials · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anupama Kulkarni AranyaDepartment of Biomaterials and Biomimetics, New York University College of Dentistry, 433 First Avenue, New York, New York, 10010.
Smruti PushalkarDepartment of Basic Science and Craniofacial Biology, New York University College of Dentistry, 345 E 24th Street, New York, New York, 10010.
Minglei ZhaoDepartment of Biomaterials and Biomimetics, New York University College of Dentistry, 433 First Avenue, New York, New York, 10010.
Racquel Z LeGerosDepartment of Biomaterials and Biomimetics, New York University College of Dentistry, 433 First Avenue, New York, New York, 10010.
Yu ZhangDepartment of Biomaterials and Biomimetics, New York University College of Dentistry, 433 First Avenue, New York, New York, 10010.
Deepak SaxenaDepartment of Basic Science and Craniofacial Biology, New York University College of Dentistry, 345 E 24th Street, New York, New York, 10010.
New York University · US

Funding

Biomaterials (Mf/Zn/F-BCPs) for osteoporosis therapyR01AR056208 · NIAMS · NEW YORK UNIVERSITY · PI ZHANG, YU · 2008 to 2012
$3.2M
Graded Zirconia Structures for Resistance to Chipping, Delamination, and FatigueR01DE017925 · NIDCR · NEW YORK UNIVERSITY · PI ZHANG, YU · 2007 to 2016
$3.0M
FISH "N" Chips: A Microfluidic Processor for Isolating and Analyzing MicrobesR01DE020891 · NIDCR · SANDIA CORP-SANDIA NATIONAL LABORATORIES · PI SINGH, ANUP K. · 2009 to 2012
$1.8M
Bacterial colonization, inflammation and its role in carcinogenesisR03DE019178 · NIDCR · NEW YORK UNIVERSITY · PI SAXENA, DEEPAK · 2010 to 2011
$243k
NIAMS NIH HHS R01 AR056208NIDCR NIH HHS R01 DE017925NIDCR NIH HHS R01 DE020891NIDCR NIH HHS R03 DE019178
6 · The paper itself

Abstract

Various surface modifications have been tried for enhancing osseointegration of the dental implants like mechanical and/or chemical treatments and deposition of calcium phosphate coatings. The objective of this research was to develop calcium-phosphate based thin coatings with antibacterial and bioactive properties for potential application in dental implants. Titanium (Ti) discs were immersed in different calcifying solutions: CaP (positive control), F-CaP, Zn-CaP, and FZn-CaP and incubated for 24 h. Negative control was uncoated Ti discs. Coated surfaces were characterized using X-ray diffraction, scanning electron microscopy and energy dispersive spectroscopy. Antibacterial properties were tested using Porphyromonas gingivalis because of its strong association with periodontal and peri-implant infections. Bacterial adhesion and colonization were studied at different timepoints. The coated surfaces had compositional characteristics similar to that of bone mineral and they inhibited the growth, colonization and adherence of P. gingivalis, resulted in reduced thickness of biofilms and bacterial inhibition in the culture medium as compared to the positive and negative controls (p < 0.05). There was no significant difference between the experimental groups (p > 0.05). It has been previously demonstrated that these coatings have excellent in vitro bioactivity (formed carbonate hydroxyapatite when immersed in a simulated body fluid). Such coatings can enhance osseointegration and prevent infection in implants, thereby improving the success rates of implants. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 2218-2227, 2017.

Indexed as

Anti-Bacterial AgentsBacteroidaceae InfectionsBiofilmsCalcium PhosphatesCoated Materials, BiocompatibleDental ImplantsDurapatiteHumansPorphyromonas gingivalisSurface PropertiesTitaniumX-Ray DiffractionAnti-Bacterial Agentscalcium phosphateCalcium PhosphatesCoated Materials, BiocompatibleDental ImplantsDurapatiteTitaniumantibacterialbioactivitydental implantimplant coatingsPorphyromonas gingivalis

Identifiers

PMID28380669
PMCPMC5488321
OpenAlexW2605339559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.