ArticlePloS one2017
Maternal age and child morbidity: A Danish national cohort study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Causes of embryo implantation failure: A systematic review and metaanalysis of procedures to increase embryo implantation potential.Frontiers in endocrinology · 2024Pooled it
- Risk factors for severe outcomes of respiratory syncytial virus infection in children: a nationwide cohort study in Sweden.The Lancet regional health. Europe · 2025Article
- Neighborhood-level heterogeneity in childhood morbidity through generalized linear mixed models.Frontiers in public health · 2025Article
- Ovarian Morphometric and Histologic Characteristics and Correlation with Clinical Factors: A Cross-Sectional Study.Journal of personalized medicine · 2023Article
- Is there any association between undesired children and health status of under-five children? Analysis of a nationally representative sample from Bangladesh.BMC pediatrics · 2022Article
- Maternal advanced age, single parenthood, and ART increase the risk of child morbidity up to five years of age.BMC pediatrics · 2022Article
- Article
- Association between Maternal High-Risk Fertility Behavior and Childhood Morbidity in Bangladesh: A Nationally Representative Cross-Sectional Survey.The American journal of tropical medicine and hygiene · 2019Article
- The impact of advanced maternal age on the outcomes of very low birth weight preterm infants.Medicine · 2019Observational
- Predictors of mercury, lead, cadmium and antimony status in Norwegian never-pregnant women of fertile age.PloS one · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe mean age at delivery has increased over the latest half of a century. Women of advanced maternal age have increased obstetrical risks and increased risk of chromosomal abnormalities and some other specified diagnoses in the offspring. The aim of this study was to assess the association between maternal age and overall child morbidity according to main diagnosis groups. MATERIAL AND
methodsWe conducted a national cohort study including 352 027 live firstborn singleton children. The children were born between Jan 1994 and Dec 2009 and followed to Dec 2012. Children were divided into groups according to maternal age: 15-24, 25-29, 30-34, and 35+ years. Poisson regression analyses calculated adjusted incidence rate ratios (IRR) of child morbidities according to main diagnoses groups A-Q of the International Classification of Disease 10 with adjustment for year of birth, body mass index, smoking, and mother's level of education.
resultsAverage follow-up time was 11 years. Compared to children born to women 25-29 years, firstborn children to mothers aged 35+ had higher child morbidity in 8 of 19 main diagnosis groups and firstborn children to mothers 15-24 years had higher child morbidity in 12 of 19 main diagnosis groups. Thus, for a majority of diseases a U-shaped correlation was found, with lowest rates in women 25-29 years.
conclusionFirstborn children to both older and younger mothers have higher overall morbidity as compared to children born by mothers 25-29 years.
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