Evidence map›Paper›PMID 28379953›Full record

ArticlePloS one2017

Aspergillus hancockii sp. nov., a biosynthetically talented fungus endemic to southeastern Australian soils.

John I Pitt, Lene Lange, Alastair E Lacey, Daniel Vuong, David J Midgley, Paul Greenfield, Mark I Bradbury, Ernest Lacey, Peter K Busk, Bo Pilgaard and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ergot Alkaloids Contribute to the Pathogenic Potential of the FungusApplied and environmental microbiology · 2023
    Article
  10. Genomic insights intoFrontiers in microbiology · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Taxonomy ofStudies in mycology · 2019
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

John I PittCommonwealth Scientific and Industrial Research Organisation, North Ryde, Australia.ORCID http://orcid.org/0000-0002-6646-6829
Lene LangeDepartment of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark.
Alastair E LaceyMicrobial Screening Technologies, Smithfield, Australia.
Daniel VuongMicrobial Screening Technologies, Smithfield, Australia.
David J MidgleyCommonwealth Scientific and Industrial Research Organisation, North Ryde, Australia.
Paul GreenfieldCommonwealth Scientific and Industrial Research Organisation, North Ryde, Australia.
Mark I BradburyCommonwealth Scientific and Industrial Research Organisation, North Ryde, Australia.
Ernest LaceyMicrobial Screening Technologies, Smithfield, Australia.
Peter K BuskDepartment of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark.
Bo PilgaardDepartment of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark.
Yit-Heng ChooiSchool of Chemistry and Biochemistry, University of Western Australia, Crawley, Australia.
Andrew M PiggottDepartment of Chemistry and Biomolecular Sciences, Macquarie University, Sydney NSW, Australia.
Commonwealth Scientific and Industrial Research Organisation · AUTechnical University of Denmark · DKMacquarie University · AUThe University of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus hancockii sp. nov., classified in Aspergillus subgenus Circumdati section Flavi, was originally isolated from soil in peanut fields near Kumbia, in the South Burnett region of southeast Queensland, Australia, and has since been found occasionally from other substrates and locations in southeast Australia. It is phylogenetically and phenotypically related most closely to A. leporis States and M. Chr., but differs in conidial colour, other minor features and particularly in metabolite profile. When cultivated on rice as an optimal substrate, A. hancockii produced an extensive array of 69 secondary metabolites. Eleven of the 15 most abundant secondary metabolites, constituting 90% of the total area under the curve of the HPLC trace of the crude extract, were novel. The genome of A. hancockii, approximately 40 Mbp, was sequenced and mined for genes encoding carbohydrate degrading enzymes identified the presence of more than 370 genes in 114 gene clusters, demonstrating that A. hancockii has the capacity to degrade cellulose, hemicellulose, lignin, pectin, starch, chitin, cutin and fructan as nutrient sources. Like most Aspergillus species, A. hancockii exhibited a diverse secondary metabolite gene profile, encoding 26 polyketide synthase, 16 nonribosomal peptide synthase and 15 nonribosomal peptide synthase-like enzymes.

Indexed as

AspergillusDNA, FungalFungiMultigene FamilyPhylogenyQueenslandSequence Analysis, DNASoilDNA, FungalSoil

Identifiers

PMID28379953
PMCPMC5381763
OpenAlexW2604884057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.