Evidence map›Paper›PMID 28379717›Full record

ArticleAmerican journal of respiratory and critical care medicine2017

Accounting for Patient Preferences Regarding Life-Sustaining Treatment in Evaluations of Medical Effectiveness and Quality.

Allan J Walkey, Amber E Barnato, Renda Soylemez Wiener, Brahmajee K Nallamothu

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Allan J Walkey1 Division of Pulmonary and Critical Care Medicine, the Pulmonary Center, and.ORCID 0000-0003-4685-6894
Amber E Barnato3 Section of Decision Sciences, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Renda Soylemez Wiener1 Division of Pulmonary and Critical Care Medicine, the Pulmonary Center, and.
Brahmajee K Nallamothu6 Division of Cardiovascular Medicine and Center for Health Outcomes and Policy, University of Michigan Medical School, Ann Arbor, Michigan.

Funding

Hospital Enhancement of Resuscitation Outcomes for In-Hospital Cardiac Arrest (HER01HL123980 · NHLBI · SAINT LUKE'S HOSPITAL · PI CHAN, PAUL SHEUNG-YAN, NALLAMOTHU, BRAHMAJEE K · 2014 to 2018
$2.7M
Atrial Fibrillation in Sepsis: Patient Outcomes and Provider Practice PatternsK01HL116768 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2013 to 2017
$742k
NHLBI NIH HHS K01 HL116768NHLBI NIH HHS R01 HL123980
6 · The paper itself

Abstract

The importance of understanding patient preferences for life-sustaining treatment is well described for individual clinical decisions; however, its role in evaluations of healthcare outcomes and quality has received little attention. Decisions to limit life-sustaining therapies are strongly associated with high risks for death in ways that are unaccounted for by routine measures of illness severity. However, this essential information is generally unavailable to researchers, with the potential for spurious inferences. This may lead to "confounding by unmeasured patient preferences" (a type of confounding by indication) and has implications for assessments of treatment effectiveness and healthcare quality, especially in acute and critical care settings in which risk for death and adverse events are high. Through a collection of case studies, we explore the effect of unmeasured patient resuscitation preferences on issues critical for researchers and research consumers to understand. We then propose strategies to more consistently elicit, record, and harmonize documentation of patient preferences that can be used to attenuate confounding by unmeasured patient preferences and provide novel opportunities to improve the patient centeredness of medical care for serious illness.

Indexed as

AdultAdvance Care PlanningAgedAged, 80 and overDecision MakingFemaleHumansMaleMiddle AgedPatient PreferencePatient SatisfactionQuality of Health CareQuality of LifeTreatment OutcomeUnited Statesend-of-life careepidemiologic biasesquality of healthcare

Identifiers

PMID28379717
PMCPMC5649985

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.