Evidence map›Paper›PMID 28379705›Full record

ArticleJournal of natural products2017

Karmitoxin: An Amine-Containing Polyhydroxy-Polyene Toxin from the Marine Dinoflagellate Karlodinium armiger.

Silas Anselm Rasmussen, Sofie Bjørnholt Binzer, Casper Hoeck, Sebastian Meier, Livia Soman de Medeiros, Nikolaj Gedsted Andersen, Allen Place, Kristian Fog Nielsen, Per Juel Hansen, Thomas Ostenfeld Larsen

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 46 citations in OpenAlex.

  1. The Chemistry of Phytoplankton.Chemical reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Silas Anselm RasmussenDepartment of Biotechnology and Biomedicine, Technical University of Denmark , Søltofts Plads Building 221, DK-2800 Kgs. Lyngby, Denmark.
Sofie Bjørnholt BinzerMarine Biological Section, Department of Biology, University of Copenhagen , Strandpromenaden 5, DK-3000 Helsingør, Denmark.
Casper HoeckDepartment of Chemistry, Technical University of Denmark , Kemitorvet Building 207, DK-2800 Kgs. Lyngby, Denmark.
Sebastian MeierDepartment of Chemistry, Technical University of Denmark , Kemitorvet Building 207, DK-2800 Kgs. Lyngby, Denmark.ORCID 0000-0003-3761-3217
Livia Soman de MedeirosFaculty of Pharmaceutical Sciences, University of São Paulo , São Paulo, 05508-000, Brazil.
Nikolaj Gedsted AndersenNational Veterinary Institute, Technical University of Denmark , Bülowsvej 27, DK-1870 Frederiksberg C, Denmark.
Allen PlaceUniversity of Maryland Center for Environmental Research , Institute of Marine and Environmental Technology, 701 E. Pratt Street, Baltimore, Maryland 21202, United States.
Kristian Fog NielsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark , Søltofts Plads Building 221, DK-2800 Kgs. Lyngby, Denmark.
Per Juel HansenMarine Biological Section, Department of Biology, University of Copenhagen , Strandpromenaden 5, DK-3000 Helsingør, Denmark.
Thomas Ostenfeld LarsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark , Søltofts Plads Building 221, DK-2800 Kgs. Lyngby, Denmark.ORCID 0000-0002-3362-5707
Technical University of Denmark · DKUniversity of Copenhagen · DKUniversidade de São Paulo · BRUniversity of Maryland, Baltimore · US

Funding

Translation regulation of gene expression in toxic dinoflagellatesR01ES021949 · NIEHS · CENTER FOR ENVIRONMENTAL SCIENCE · PI JAGUS, ROSEMARY, PLACE, ALLEN RICHARD · 2012 to 2016
$645k
NIEHS NIH HHS R01 ES021949
6 · The paper itself

Abstract

Marine algae from the genus Karlodinium are known to be involved in fish-killing events worldwide. Here we report for the first time the chemistry and bioactivity of a natural product from the newly described mixotrophic dinoflagellate Karlodinium armiger. Our work describes the isolation and structural characterization of a new polyhydroxy-polyene named karmitoxin. The structure elucidation work was facilitated by use of

Indexed as

AminesAnimalsDinoflagellidaMagnetic Resonance SpectroscopyMarine ToxinsMolecular StructurePolyenesAmineskarmitoxinMarine ToxinsPolyenes

Identifiers

PMID28379705
PMCPMC6446557
OpenAlexW2604591414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.