Evidence map›Paper›PMID 28379431›Full record

Observational studyNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2017

Barriers to living donor kidney transplantation in the United Kingdom: a national observational study.

Diana A Wu, Matthew L Robb, Christopher J E Watson, John L R Forsythe, Charles R V Tomson, John Cairns, Paul Roderick, Rachel J Johnson, Rommel Ravanan, Damian Fogarty and 6 more

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness of a culturally competent care intervention in reducing disparities in Hispanic live donor kidney transplantation: A hybrid trial.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Trial
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  4. Review
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  10. Review
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  12. Sex and Gender Disparities in Kidney Transplantation.Advances in kidney disease and health · 2025
    Review
  13. Review
  14. Factors Influencing Kidney Transplantation Experiences for Patients From Culturally and Linguistically Diverse Backgrounds: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Diana A WuTransplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Matthew L RobbNHS Blood and Transplant, Bristol, UK.
Christopher J E WatsonDepartment of Surgery, University of Cambridge and the NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
John L R ForsytheTransplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Charles R V TomsonDepartment of Renal Medicine, Freeman Hospital, Newcastle upon Tyne, UK.
John CairnsDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Paul RoderickPrimary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Rachel J JohnsonNHS Blood and Transplant, Bristol, UK.
Rommel RavananDepartment of Renal Medicine, Southmead Hospital, Bristol, UK.
Damian FogartyRegional Nephrology and Transplant Centre, Belfast Health and Social Care Trust, Belfast, UK.
Clare BradleyHealth Psychology Research Unit, Royal Holloway, University of London, Egham, UK.
Andrea GibbonsHealth Psychology Research Unit, Royal Holloway, University of London, Egham, UK.
Wendy MetcalfeTransplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Heather DraperHealth Sciences, University of Warwick, Conventry, UK (author has moved institutions since acceptance of the article).
Andrew J BradleyDepartment of Surgery, University of Cambridge and the NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
Gabriel C OniscuTransplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Edinburgh Royal Infirmary · GBNHS Blood and Transplant · GBRoyal Holloway University of London · GBBelfast Health and Social Care Trust · GBFreeman Hospital · GBLondon School of Hygiene & Tropical Medicine · GBNIHR Cambridge Biomedical Research CentreSouthmead Hospital · GBUniversity of Cambridge · GBUniversity of Southampton · GBUniversity of Warwick · GB

Funding

Department of Health RP-PG-0109-10116
6 · The paper itself

Abstract

backgroundLiving donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK.

methodsA total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified.

resultsOf the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08-0.17], P < 0.0001 for 65-75 years versus 18-34 years}; Asian ethnicity [OR 0.55 (95% CI 0.39-0.77), P = 0.0006 versus White]; Black ethnicity [OR 0.64 (95% CI 0.42-0.99), P = 0.047 versus White]; divorced, separated or widowed [OR 0.63 (95% CI 0.46-0.88), P = 0.030 versus married]; no qualifications [OR 0.55 (95% CI 0.42-0.74), P < 0.0001 versus higher education qualifications]; no car ownership [OR 0.51 (95% CI 0.37-0.72), P = 0.0001] and no home ownership [OR 0.65 (95% CI 0.85-0.79), P = 0.002]. The odds of LDKT varied significantly between countries in the UK.

conclusionsAmong patients undergoing kidney transplantation in the UK, there are significant age, ethnic, socio-economic and geographic disparities in the utilization of LDKT. Further work is needed to explore the potential for targeted interventions to improve equity in living donor transplantation.

Indexed as

Donor SelectionHealth Knowledge, Attitudes, PracticeKidney TransplantationLiving DonorsTissue and Organ ProcurementAdolescentAdultAgedBlack or African AmericanCommunication BarriersFemaleHumansMaleMiddle AgedProspective StudiesUnited Kingdominequitykidney transplantationliving donorpre-emptive transplantationsociodemographic disparities

Identifiers

PMID28379431
PMCPMC5427518
OpenAlexW2603861185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.