Evidence map›Paper›PMID 28379325›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2017

Change in Bone Mineral Density During Weight Loss with Resistance Versus Aerobic Exercise Training in Older Adults.

Kristen M Beavers, Daniel P Beavers, Sarah B Martin, Anthony P Marsh, Mary F Lyles, Leon Lenchik, Sue A Shapses, Barbara J Nicklas

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  5. Effect of Exercise Modality During Weight Loss on Bone Health in Older Adults With Obesity and Cardiovascular Disease or Metabolic Syndrome: A Randomized Controlled Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
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  13. New Insights into Calorie Restriction Induced Bone Loss.Endocrinology and metabolism (Seoul, Korea) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kristen M BeaversDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
Daniel P BeaversDepartment of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Sarah B MartinDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
Anthony P MarshDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
Mary F LylesDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Winston-Salem, North Carolina.
Leon LenchikDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Sue A ShapsesDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey.
Barbara J NicklasDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Winston-Salem, North Carolina.
Wake Forest University · USWinston-Salem/Forsyth County Schools · USRutgers, The State University of New Jersey · US

Funding

Effect of fat loss on functional and cardiovascular benefits of aerobic exerciseR01HL093713 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J · 2009 to 2013
$3.4M
Effect of Exercise Modality During Weight Loss on Bone Health in Older AdultsK01AG047921 · NIA · WAKE FOREST UNIVERSITY · PI BEAVERS, KRISTEN MARIE · 2015 to 2018
$463k
NHLBI NIH HHS R01 HL093713NIA NIH HHS K01 AG047921
6 · The paper itself

Abstract

backgroundTo examine the effect of exercise modality during weight loss on hip and spine bone mineral density (BMD) in overweight and obese, older adults.

methodsThis analysis compared data from two 5-month, randomized controlled trials of caloric restriction (CR; inducing 5-10% weight loss) with either resistance training (RT) or aerobic training (AT) in overweight and obese, older adults. Participants in the RT + CR study underwent 3 days/week of 8 upper/lower body exercises (3 sets, 10 repetitions at 70% 1 RM) and participants in the AT+CR study underwent 4 days/week of treadmill walking (30 min at 65-70% heart rate reserve). BMD at the total hip, femoral neck, and lumbar spine was assessed via dual-energy X-ray absorptiometry at baseline and 5 months.

resultsA total of 123 adults (69.4 ± 3.5 years, 67% female, 81% Caucasian) participated in the RT+CR (n = 60) and AT+CR (n = 63) interventions. Average weight loss was 5.7% (95% CI: 4.6-6.7%) and 8.2% (95% CI: 7.2-9.3%) in RT+CR and AT+CR groups, respectively. After adjustment for age, gender, race, baseline BMI and BMD, and weight change, differential treatment effects were observed for total hip and femoral neck (both p < .05), but not lumbar spine. Total hip (1.83 [-3.90, 7.55] mg/cm2) and femoral neck (9.14 [-0.70, 18.98] mg/cm2) BMD was unchanged in RT+CR participants, and modestly decreased in AT+CR participants (total hip: -7.01 [-12.73, -1.29] mg/cm2; femoral neck: -5.36 [-14.92, 4.20] mg/cm2).

conclusionsResults suggest performing resistance, rather than aerobic, training during CR may attenuate loss of hip and femoral neck BMD in overweight and obese older adults. Findings warrant replication from a long-term, adequately powered, RCT.

Indexed as

AgingAbsorptiometry, PhotonAgedBone DensityExerciseFemaleFemur NeckFollow-Up StudiesHumansMaleObesityPrognosisResistance TrainingRetrospective StudiesTime FactorsWeight LossBone agingCaloric restrictionExerciseObesity

Identifiers

PMID28379325
PMCPMC5861903
OpenAlexW2605265116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.