ArticleMolecular plant pathology2018
The pathogenic development of Sclerotinia sclerotiorum in soybean requires specific host NADPH oxidases.
Article in Molecular plant pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 72 citations in OpenAlex.
- The Roles of Plant MicroRNAs in Defence Against Pathogens.Molecular plant pathology · 2026Review
- Microorganisms' perception, scavenging, and adaptation to reactive oxygen species signals in microbe-plant interactions.World journal of microbiology & biotechnology · 2025Review
- A retrotransposon insertion upstream of Arabidopsis thaliana CRK8 receptor-like kinase modulates a trade-off between pathogen defense and salt tolerance.The Plant journal : for cell and molecular biology · 2025Article
- Trans-Kingdom sRNA Silencing inPathogens (Basel, Switzerland) · 2025Review
- Identification of VcRBOH genes in blueberry and functional characterization of VcRBOHF in plant defense.BMC genomics · 2025Article
- The non-specific phospholipase C of common bean PvNPC4 modulates roots and nodule development.PloS one · 2025Article
- Comparative insights into soybean and other oilseed crops' defense mechanisms againstFrontiers in plant science · 2025Review
- A comprehensive review of soybean RNL and TIR domain proteins.Plant molecular biology · 2024Review
- Challenges and Opportunities Arising from Host-International journal of molecular sciences · 2024Review
- Transcriptomic Profiling of Sugarcane White Leaf (SCWL) Canes during Maturation Phase.Plants (Basel, Switzerland) · 2024Article
- Elucidation of mechanisms underlying active oxygen burst inFrontiers in microbiology · 2024Article
- Soybean transporter AAT Rhg1 abundance increases along the nematode migration path and impacts vesiculation and ROS.Plant physiology · 2023Article
- Article
- Genome-Wide Association Studies Reveal Novel Loci for Herbivore Resistance in Wild Soybean (International journal of molecular sciences · 2022Article
- Targeting the alternative oxidase (AOX) for human health and food security, a pharmaceutical and agrochemical target or a rescue mechanism?The Biochemical journal · 2022Review
- Sunflower resistance against Sclerotinia sclerotiorum is potentiated by selenium through regulation of redox homeostasis and hormones signaling pathways.Environmental science and pollution research international · 2022Article
- Roles of small RNAs in crop disease resistance.Stress biology · 2021Review
- Host-Induced Gene Silencing of aFrontiers in plant science · 2021Article
- The bZIP Transcription Factor GmbZIP15 Negatively Regulates Salt- and Drought-Stress Responses in Soybean.International journal of molecular sciences · 2020Article
- Sclerotinia sclerotiorum utilizes host-derived copper for ROS detoxification and infection.PLoS pathogens · 2020Article
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8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant membrane-localized NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), play crucial roles in various cellular activities, including plant disease responses, and are a major source of reactive oxygen species (ROS). Sclerotinia sclerotiorum is a cosmopolitan fungal pathogen that causes Sclerotinia stem rot (SSR) in soybean. Via a key virulence factor, oxalic acid, it induces programmed cell death (PCD) in the host plant, a process that is reliant on ROS generation. In this study, using protein sequence similarity searches, we identified 17 soybean RBOHs (GmRBOHs) and studied their contribution to SSR disease development, drought tolerance and nodulation. We clustered the soybean RBOH genes into six groups of orthologues based on phylogenetic analysis with their Arabidopsis counterparts. Transcript analysis of all 17 GmRBOHs revealed that, of the six identified groups, group VI (GmRBOH-VI) was specifically and drastically induced following S. sclerotiorum challenge. Virus-induced gene silencing (VIGS) of GmRBOH-VI using Bean pod mottle virus (BPMV) resulted in enhanced resistance to S. sclerotiorum and markedly reduced ROS levels during disease development. Coincidently, GmRBOH-VI-silenced plants were also found to be drought tolerant, but showed a reduced capacity to form nodules. Our results indicate that the pathogenic development of S. sclerotiorum in soybean requires the active participation of specific host RBOHs, to induce ROS and cell death, thus leading to the establishment of disease.
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