ArticleScientific reports2017
Functionalized core-shell hydrogel microsprings by anisotropic gelation with bevel-tip capillary.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 46 citations in OpenAlex.
- From flow to form: structuring and patterning hydrogels using microfluidic approaches.Lab on a chip · 2026Review
- Self-Oscillating Helix Showing Amplified Winding and Unwinding Motions.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Liquid Metal-Polymer Hydrogel Composites for Sustainable Electronics: A Review.Molecules (Basel, Switzerland) · 2025Review
- Capacitance of Flexible Polymer/Graphene Microstructures with High Mechanical Strength.3D printing and additive manufacturing · 2024Article
- Algal Phycocolloids: Bioactivities and Pharmaceutical Applications.Marine drugs · 2023Review
- Magnetic hydrogels with ordered structure for biomedical applications.Frontiers in chemistry · 2022Review
- Magnetically Driven Micro and Nanorobots.Chemical reviews · 2021Article
- Current Status of Alginate in Drug Delivery.Advances in pharmacological and pharmaceutical sciences · 2020Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study describes a novel microfluidic-based method for the synthesis of hydrogel microsprings that are capable of encapsulating various functional materials. A continuous flow of alginate pre-gel solution can spontaneously form a hydrogel microspring by anisotropic gelation around the bevel-tip of the capillary. This technique allows fabrication of hydrogel microsprings using only simple capillaries and syringe pumps, while their complex compartmentalization characterized by a laminar flow inside the capillary can contribute to the optimization of the microspring internal structure and functionality. Encapsulation of several functional materials including magnetic-responsive nanoparticles or cell dispersed collagen for tissue scaffold was demonstrated to functionalize the microsprings. Our core-shell hydrogel microsprings have immense potential for application in a number of fields, including biological/chemical microsensors, biocompatible soft robots/microactuators, drug release, self-assembly of 3D structures and tissue engineering.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.