ReviewWorld journal of microbiology & biotechnology2017
Fomitopsis betulina (formerly Piptoporus betulinus): the Iceman's polypore fungus with modern biotechnological potential.
Review in World journal of microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 54 citations in OpenAlex.
- Anticancer Properties of Selected Wood-Inhabiting Fungi.Nutrients · 2026Review
- Free radical inhibition and total phenolic content inFrontiers in fungal biology · 2026Article
- Innovative applications of medicinal mushrooms in functional foods and nutraceuticals: a focus on health-boosting beverages.Frontiers in cellular and infection microbiology · 2025Review
- The bioactive compounds, beneficial medicinal properties, and biotechnological prospects ofFrontiers in cellular and infection microbiology · 2025Review
- Mushroom against Cancer: Aqueous Extract ofNutrients · 2024Article
- Secondary Metabolites ofJournal of fungi (Basel, Switzerland) · 2024Review
- From Nature to Design: Tailoring Pure Mycelial Materials for the Needs of Tomorrow.Journal of fungi (Basel, Switzerland) · 2024Review
- Cytotoxic activity ofContemporary oncology (Poznan, Poland) · 2024Review
- Effects ofInternational journal of molecular sciences · 2022Article
- Traditional medicinal plants in South Tyrol (northern Italy, southern Alps): biodiversity and use.Journal of ethnobiology and ethnomedicine · 2020Review
- Arsenic speciation in the bracket fungus Fomitopsis betulina from contaminated and pristine sites.Environmental geochemistry and health · 2020Article
- Antitumour effect of glucooligosaccharides obtained via hydrolysis of α-(1 → 3)-glucan from Fomitopsis betulina.Molecular biology reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Higher Basidiomycota have been used in natural medicine throughout the world for centuries. One of such fungi is Fomitopsis betulina (formerly Piptoporus betulinus), which causes brown rot of birch wood. Annual white to brownish fruiting bodies of the species can be found on trees in the northern hemisphere but F. betulina can also be cultured as a mycelium and fruiting body. The fungus has a long tradition of being applied in folk medicine as an antimicrobial, anticancer, and anti-inflammatory agent. Probably due to the curative properties, pieces of its fruiting body were carried by Ötzi the Iceman. Modern research confirms the health-promoting benefits of F. betulina. Pharmacological studies have provided evidence supporting the antibacterial, anti-parasitic, antiviral, anti-inflammatory, anticancer, neuroprotective, and immunomodulating activities of F. betulina preparations. Biologically active compounds such as triterpenoids have been isolated. The mushroom is also a reservoir of valuable enzymes and other substances such as cell wall (1→3)-α-D-glucan which can be used for induction of microbial enzymes degrading cariogenic dental biofilm. In conclusion, F. betulina can be considered as a promising source for the development of new products for healthcare and other biotechnological uses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.