ArticleSurgical endoscopy2017
Different clinical characteristics associated with acute bleeding and delayed bleeding after endoscopic submucosal dissection in patients with early gastric cancer.
Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Efficacy of Fibrin Sealants and Polyglycolic Acid Sheets in Reducing Postoperative Hemorrhage Following Gastric Endoscopic Submucosal Dissection: A Meta-analysis of Randomized and Observational Studies.Journal of gastrointestinal cancer · 2026Pooled it
- Potential of Direct Oral Anticoagulant in Bleeding After Gastric Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- Endoscopic Hand Suturing After Gastric Endoscopic Submucosal Dissection in Patients with Low to Intermediate Risk of Delayed Bleeding: A Retrospective Pilot Study.Digestive diseases and sciences · 2026Observational
- The Hedgehog Method Following Gastric Endoscopic Submucosal Dissection: Observed Postoperative Bleeding Rates Across BEST-J Risk Categories.Digestive diseases and sciences · 2026Article
- Risk of Postoperative Bleeding in Esophageal Endoscopic Submucosal Dissection for Squamous Cell Carcinoma in Patients on Antiplatelet Therapy: A Multicenter Retrospective Study in Japan.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Article
- Effect of Oral Proton-Pump Inhibitor Administration on Reducing the Delayed Bleeding Risk in 5 Upper Gastrointestinal Endoscopic Treatments.The American journal of gastroenterology · 2026Article
- Prediction of delayed bleeding after endoscopic submucosal dissection in early gastric cancer and precancerous lesions by BEST-C score.Surgical endoscopy · 2026Article
- Article
- Retrospective comparison of precutting endoscopic band ligation and endoscopic submucosal dissection for small gastric muscularis propria tumors.World journal of gastrointestinal endoscopy · 2026Article
- Effectiveness of the aspiration method in preventing delayed bleeding after gastric endoscopic submucosal dissection.Surgical endoscopy · 2026Article
- Efficacy of human-derived fibrin sealant in preventing postoperative adverse events after gastric endoscopic submucosal dissection: a retrospective multicenter study.European journal of medical research · 2025Article
- Advancements in endoscopic closure: Embracing a new era of managing complications and postprocedural defects after endoscopic submucosal dissection.World journal of gastrointestinal endoscopy · 2025Review
- Article
- Efficacy of alternate mucosa-submucosa clip closure in preventing postoperative adverse events for patients with gastric mucosal lesions after endoscopic submucosal dissection: a multicenter retrospective study.Therapeutic advances in gastroenterology · 2025Article
- Effect of sarcopenia on short-term outcomes of gastric endoscopic submucosal dissection.Surgical endoscopy · 2024Article
- A risk prediction model for delayed bleeding after ESD for gastric precancerous lesions.Surgical endoscopy · 2024Article
- Risk factors for rebleeding in gastroduodenal ulcers.Irish journal of medical science · 2024Article
- Hemostatic Effect and Mechanism of Epidermal Growth Factor-Hemostatic Powder after Endoscopic Submucosal Dissection in a Porcine Model.Gut and liver · 2023Article
- Assessment of delayed bleeding after endoscopic submucosal dissection of early-stage gastrointestinal tumors in patients receiving direct oral anticoagulants.World journal of gastroenterology · 2023Review
- Postoperative Bleeding Risk after Gastric Endoscopic Submucosal Dissection in Patients Receiving a P2Y12 Receptor Antagonist.Gut and liver · 2023Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsFew studies have classified risk factors according to the onset time of bleeding after endoscopic submucosal dissection (post-ESD bleeding).
methodsWe studied 1767 consecutive lesions in patients who underwent ESD for early gastric cancer from December 2006 through June 2016. Patients who had a remnant stomach or who had undergone reconstruction with a gastric tube were excluded. Post-ESD bleeding was classified into acute bleeding (0-5 days after ESD) and delayed bleeding (6 or more days after ESD), and the risk factors for each type of bleeding were compared.
resultsPost-ESD bleeding occurred in 150 (8.5%) of 1767 lesions. Bleeding was acute in 129 lesions (7.3%) and delayed in 21 (1.2%). Acute post-ESD bleeding was frequently associated with lesions located in the distal stomach, expanded indications or non-indicated lesions, a specimen diameter of ≥40 mm, and antithrombotic therapy. Delayed post-ESD bleeding was often associated with lesions located in the proximal stomach, hemodialysis, and antithrombotic therapy. Among 334 lesions in patients who received antithrombotic therapy, post-ESD bleeding occurred in 47 lesions (14.1%). Independent risk factors for post-ESD bleeding were a specimen diameter of ≥40 mm and treatment with 2 or more antithrombotic agents.
conclusionsAcute post-ESD bleeding and delayed post-ESD bleeding were associated with different clinical characteristics. Antithrombotic therapy is a risk factor for post-ESD bleeding in both the acute and delayed phases.
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