Evidence map›Paper›PMID 28378067›Full record

ReviewCancer immunology, immunotherapy : CII2017

Bone marrow myeloid cells in regulation of multiple myeloma progression.

Sarah E Herlihy, Cindy Lin, Yulia Nefedova

Open access · greenAbstract readReview
In one paragraph

Review in Cancer immunology, immunotherapy : CII, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarah E HerlihyTumor Microenvironment and Metastasis Program, The Wistar Institute, 3601 Spruce Street, Room 376, Philadelphia, PA, 19104, USA.
Cindy LinTumor Microenvironment and Metastasis Program, The Wistar Institute, 3601 Spruce Street, Room 376, Philadelphia, PA, 19104, USA.
Yulia NefedovaTumor Microenvironment and Metastasis Program, The Wistar Institute, 3601 Spruce Street, Room 376, Philadelphia, PA, 19104, USA. ynefedova@wistar.org.
The Wistar Institute · US

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9M
TRAINING PROGRAM IN BASIC CANCER RESEARCHT32CA009171 · NCI · WISTAR INSTITUTE · PI Alessandro Gardini · 1985 to 2026
$15.3M
Extracellular DNA in regulation of multiple myelomaR01CA196788 · NCI · WISTAR INSTITUTE · PI NEFEDOVA, YULIA · 2016 to 2020
$2.1M
Regulation of multiple myeloma by S100A9 proteinR21CA195020 · NCI · WISTAR INSTITUTE · PI NEFEDOVA, YULIA, VOGL, DAN TOBY · 2016 to 2017
$468k
NCI NIH HHS P30 CA010815NCI NIH HHS R01 CA196788NCI NIH HHS R21 CA195020NCI NIH HHS T32 CA009171
6 · The paper itself

Abstract

Survival, growth, and response to chemotherapy of cancer cells depends strongly on the interaction of cancer cells with the tumor microenvironment. In multiple myeloma, a cancer of plasma cells that localizes preferentially in the bone marrow, the microenvironment is highly enriched with myeloid cells. The majority of myeloid cells are represented by mature and immature neutrophils. The contribution of the different myeloid cell populations to tumor progression and chemoresistance in multiple myeloma is discussed.

Indexed as

Tumor EscapeAnimalsBone MarrowCarcinogenesisCell DifferentiationDrug Resistance, NeoplasmHumansImmunomodulationMultiple MyelomaMyeloid CellsNeutrophilsTumor MicroenvironmentCancerChemoresistanceMultiple myelomaMyeloid-derived suppressor cellsNeutrophilsRegulatory myeloid suppressor cells

Identifiers

PMID28378067
PMCPMC11029144
OpenAlexW2604559245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.