Evidence map›Paper›PMID 28377958›Full record

ArticleBone reports2015

Effect of vitamin D

Ahmed A Madar, Kirsten V Knutsen, Lars C Stene, Mette Brekke, Per Lagerløv, Haakon E Meyer, Helen M Macdonald

Open access · goldAbstract read
In one paragraph

Article in Bone reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Effect of isolated vitamin D supplementation on bone turnover markers in younger postmenopausal women: a randomized, double-blind, placebo-controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Vitamin DScientific reports · 2024
    Article
  10. Migration health research in Norway: a scoping review.Scandinavian journal of public health · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Serum 25(OH)D is associated with an altered bone turnover marker response after a hip fracture.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ahmed A MadarDepartment of Community Medicine, Institute of Health and Society, University of Oslo, Norway.
Kirsten V KnutsenDepartment of General Practice, Institute of Health and Society, University of Oslo, Norway.
Lars C SteneDivision of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.
Mette BrekkeDepartment of General Practice, Institute of Health and Society, University of Oslo, Norway.
Per LagerløvDepartment of General Practice, Institute of Health and Society, University of Oslo, Norway.
Haakon E MeyerDepartment of Community Medicine, Institute of Health and Society, University of Oslo, Norway; Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.
Helen M MacdonaldSchool of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK.
University of Oslo · NONorwegian Institute of Public Health · NOUniversity of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVitamin D is essential for the maintenance of calcium homeostasis and bone mineralization; and low serum 25-hydroxyvitamin D (s-25-(OH)D) concentrations are associated with increased bone turnover. However, there is a lack of randomized controlled trials that have investigated the effect of vitamin D treatment on bone turnover in immigrant populations. We aimed to investigate the effect of 16-week daily vitamin D

designDouble-blind, randomized, placebo-controlled trial.

settingImmigrant community centers in Oslo, Norway.

participants251 healthy adults aged 18-50 years with a non-Western immigrant background were recruited.

intervention16 weeks of daily oral supplementation with either 10 μg vitamin D

main outcome measuresDifference in change during the 16-week intervention between the intervention groups combined (10 or 25 μg of vitamin D

resultsA total of 214 (85%) participants completed the study. S-25-(OH)D increased from 29 nmol/L at baseline to 49 nmol/L in the intervention group with no significant change in the placebo group. However, there was no difference in change of serum P1NP (mean difference: - 1.2 μg/L (95% CI: - 5.4, 2.9, P = 0.6)) and serum CTX (mean difference: - 0.005 μg/L (95% CI: - 0.03, 0.02, P = 0.7)) between those receiving vitamin D

conclusionsSupplementation with 10 or 25 μg oral vitamin D

Indexed as

25(OH)DBone markersCTXImmigrantsP1NPRCTVitamin D supplementation

Identifiers

PMID28377958
PMCPMC5365165
OpenAlexW326642456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.