ArticleEpilepsy & behavior case reports2017
Evolution of epilepsy in hemimegalencephaly from infancy to adulthood: Case report and review of the literature.
Article in Epilepsy & behavior case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- A novel PTEN variant causing hemimegalencephaly and focal nodular heterotopias in the developing human brain.Epilepsia · 2026Article
- Refractory neonatal seizures caused by hemimegalencephaly.BMJ case reports · 2022Article
- The Most Common Lesions Detected by Neuroimaging as Causes of Epilepsy.Medicina (Kaunas, Lithuania) · 2021Review
- Article
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2 authors at 1 institution in 1 country.
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Abstract
Hemimegalencephaly (HME) is a rare disorder of cortical development with overgrowth of one cerebral hemisphere. Patients have intellectual delay, hemiparesis and severe epilepsy. Drug-resistant epilepsy is often treated with a hemispherectomy. We review the literature on HME natural history and report a 26-year-old man with HME who did not undergo hemispherectomy in childhood with recurrent focal convulsive or non-convulsive status epilepticus. Few patients with HME have been followed into adulthood. Reported adult cases have milder epilepsy or underwent hemispherectomy in childhood. Patients surviving to adulthood have poor outcomes, regardless of treatment method, although seizure burden is improved with hemispherectomy.
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