ArticleFrontiers in physiology2017
Toward Precision Healthcare: Context and Mathematical Challenges.
Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Sorting out and navigating uncertainty in precision medicine.History and philosophy of the life sciences · 2026Article
- Observer- and sequence variability in personalized 4D flow MRI-based cardiovascular models.Scientific reports · 2025Article
- HyperTraPS-CT: Inference and prediction for accumulation pathways with flexible data and model structures.PLoS computational biology · 2024Article
- Article
- Towards Ideal Health Ecosystem With Artificial Intelligence-Driven Medical Services in India: An Overview.Cureus · 2023Review
- Editorial: Data science and health economics in precision public health.Frontiers in public health · 2022Article
- Opportunities in precision psychiatry using PET neuroimaging in psychosis.Neurobiology of disease · 2019Review
- Evolving mtDNA populations within cells.Biochemical Society transactions · 2019Review
- Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings.Nature communications · 2019Article
- Challenges and solutions in patient treatment strategies for stage II colon cancer.Gastroenterology report · 2019Review
- Precision identification of high-risk phenotypes and progression pathways in severe malaria without requiring longitudinal data.NPJ digital medicine · 2019Article
- From free text to clusters of content in health records: an unsupervised graph partitioning approach.Applied network science · 2019Article
- Big Data's Role in Precision Public Health.Frontiers in public health · 2018Review
- Standardized screening for periodontitis as an integral part of multidisciplinary management of adults with type 2 diabetes: an observational cross-sectional study of cohorts in the USA and UK.BMJ open diabetes research & care · 2017Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Precision medicine refers to the idea of delivering the right treatment to the right patient at the right time, usually with a focus on a data-centered approach to this task. In this perspective piece, we use the term "precision healthcare" to describe the development of precision approaches that bridge from the individual to the population, taking advantage of individual-level data, but also taking the social context into account. These problems give rise to a broad spectrum of technical, scientific, policy, ethical and social challenges, and new mathematical techniques will be required to meet them. To ensure that the science underpinning "precision" is robust, interpretable and well-suited to meet the policy, ethical and social questions that such approaches raise, the mathematical methods for data analysis should be transparent, robust, and able to adapt to errors and uncertainties. In particular, precision methodologies should capture the complexity of data, yet produce tractable descriptions at the relevant resolution while preserving intelligibility and traceability, so that they can be used by practitioners to aid decision-making. Through several case studies in this domain of precision healthcare, we argue that this vision requires the development of new mathematical frameworks, both in modeling and in data analysis and interpretation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.