ArticleNature communications2017
Rotiferan Hox genes give new insights into the evolution of metazoan bodyplans.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 199 citations in OpenAlex.
- ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026Article
- Patterns of Conservation and Loss of Hox Genes in Xenacoelomorph Lineage Since Divergence From Last Common Bilaterian Ancestor.Genome biology and evolution · 2026Article
- Anterior-posterior patterning in the chaetognath Spadella cephaloptera informs bilaterian nervous system and tail evolution.Communications biology · 2025Article
- Article
- The perplexing body plan of arrow worms decoded.Nature · 2025Article
- Article
- A transcriptomic examination of encased rotifer embryos reveals the developmental trajectory leading to long-term dormancy; are they "animal seeds"?BMC genomics · 2024Article
- A giant stem-group chaetognath.Science advances · 2024Article
- Genomic and transcriptomic survey of bryozoan Hox and ParaHox genes with emphasis on phylactolaemate bryozoans.BMC genomics · 2023Article
- Highly efficient CRISPR-mediated gene editing in a rotifer.PLoS biology · 2023Article
- Comparative Genomics Reveals Evolutionary Drivers of Sessile Life and Left-right Shell Asymmetry in Bivalves.Genomics, proteomics & bioinformatics · 2022Article
- The Genome of the Marine Rotifer Brachionus manjavacas: Genome-Wide Identification of 310 G Protein-Coupled Receptor (GPCR) Genes.Marine biotechnology (New York, N.Y.) · 2022Article
- Diversification and Functional Evolution of HOX Proteins.Frontiers in cell and developmental biology · 2022Review
- Genomics and transcriptomics of epizoic Seisonidea (Rotifera, syn. Syndermata) reveal strain formation and gradual gene loss with growing ties to the host.BMC genomics · 2021Article
- Taxonomic Sampling and Rare Genomic Changes Overcome Long-Branch Attraction in the Phylogenetic Placement of Pseudoscorpions.Molecular biology and evolution · 2021Article
- Loss of intermediate regions of perpendicular body axes contributed to miniaturization of tardigrades.Proceedings. Biological sciences · 2020Article
- Developmental gene expression as a phylogenetic data class: support for the monophyly of Arachnopulmonata.Development genes and evolution · 2020Article
- Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- The genome, transcriptome, and proteome of the fish parasite Pomphorhynchus laevis (Acanthocephala).PloS one · 2020Article
- Neurons and Glia Cells in Marine Invertebrates: An Update.Frontiers in neuroscience · 2020Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phylum Rotifera consists of minuscule, nonsegmented animals with a unique body plan and an unresolved phylogenetic position. The presence of pharyngeal articulated jaws supports an inclusion in Gnathifera nested in the Spiralia. Comparison of Hox genes, involved in animal body plan patterning, can be used to infer phylogenetic relationships. Here, we report the expression of five Hox genes during embryogenesis of the rotifer Brachionus manjavacas and show how these genes define different functional components of the nervous system and not the usual bilaterian staggered expression along the anteroposterior axis. Sequence analysis revealed that the lox5-parapeptide, a key signature in lophotrochozoan and platyhelminthean Hox6/lox5 genes, is absent and replaced by different signatures in Rotifera and Chaetognatha, and that the MedPost gene, until now unique to Chaetognatha, is also present in rotifers. Collectively, our results support an inclusion of chaetognaths in gnathiferans and Gnathifera as sister group to the remaining spiralians.Rotifers are microscopic animals with an unusual, nonsegmented body plan consisting of a head, trunk and foot. Here, Fröbius and Funch investigate the role of Hox genes-which are widely used in animal body plan patterning-in rotifer embryogenesis and find non-canonical expression in the nervous system.
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