ArticlemBio2017
Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 228 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
228citing papers in PubMed, 2 pooled it
29.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
228 citing papers in PubMed, 2 syntheses or guidelines pooled it, 383 citations in OpenAlex.
- Pooled it
- What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2019Pooled it
- Detection of aEmerging microbes & infections · 2026Article
- Aminopeptidase N is a receptor for hedgehog merbecoviruses.Nature microbiology · 2026Article
- Directed evolution of a stem-helix-targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity.PLoS pathogens · 2026Article
- The role of DPP4 in viral infections: from receptor biology to antiviral target.Archives of virology · 2026Review
- Development of a recombinant single-cycle influenza viral vector as an intranasal vaccine against SARS-CoV-2.Scientific reports · 2026Article
- Optimization of environmental air sampling for viral metagenomics in a cave-roosting bat assemblage.One health outlook · 2026Article
- Molecular Detection of Alpha- and Betacoronaviruses in Bats from Afar Region, Ethiopia.Veterinary medicine and science · 2026Article
- A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses.Nature communications · 2026Article
- Structural basis for human DPP4 receptor recognition by MERS-like coronaviruses 2014-422 and GX2012.PLoS pathogens · 2026Article
- MERS-CoV accessory ORF proteins in innate immune evasion: an evidence-graded functional framework.Frontiers in immunology · 2026Review
- Local and introduced lineages drive MERS-CoV recombination in Egyptian camels.Journal of virology · 2025Article
- Development of a Recombinant Single-Cycle Influenza Viral Vector as an Intranasal Vaccine against SARS-CoV-2 and SARS-like Betacoronaviruses.bioRxiv : the preprint server for biology · 2025Article
- Clade C MERS-CoV camel strains vary in protease utilization during viral entry.bioRxiv : the preprint server for biology · 2025Article
- Directed evolution of a stem-helix-targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity.bioRxiv : the preprint server for biology · 2025Article
- Characterization of a MERS-related betacoronavirus in Danish brown long-eared bats (Plecotus auritus).Virology journal · 2025Article
- Article
- Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology.Annals of the New York Academy of Sciences · 2025Review
- Identification and characterization of novel bat coronaviruses in Spain.PLoS pathogens · 2025Article
168 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 6 institutions in 2 countries.
S J AnthonyCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA sja2127@cumc.columbia.edu.
K GilardiOne Health Institute and Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California, USA.
V D MenacheryDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
T GoldsteinOne Health Institute and Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California, USA.
B SsebideGorilla Doctors, c/o MGVP, Inc., Davis, California, USA.
R MbabaziGorilla Doctors, c/o MGVP, Inc., Davis, California, USA.
I Navarrete-MaciasCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
E LiangCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
H WellsCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
A HicksCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
A PetrosovCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
D K ByarugabaMakerere University Walter Reed Project, Kampala, Uganda.
K DebbinkDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
K H DinnonDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
T ScobeyDepartment of Epidemiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
S H RandellDepartment of Cell Biology and Physiology and Marsico Lung Institute/Cystic Fibrosis Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
B L YountDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
M CranfieldOne Health Institute and Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California, USA.
C K JohnsonOne Health Institute and Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California, USA.
R S BaricDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
W I LipkinCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
J A K MazetOne Health Institute and Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California, USA.
University of North Carolina at Chapel Hill · USColumbia University · USUniversity of California, Davis · USGorilla Doctors · USEcoHealth Alliance · USMakerere University Walter Reed Project · UG
Funding
Translational CoreU19AI109761 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARIC, RALPH S · 2014 to 2018
$32.6MVector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5MMechanisms of MERS-CoV Entry, Cross-species Transmission and PathogenesisR01AI110700 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARIC, RALPH S, LI, FANG · 2015 to 2024
$7.4MSystems Based Analysis of Host Factors that Contribute to Aging PathogenesisR00AG049092 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MENACHERY, VINEET D · 2017 to 2019
$736kSystems Based Analysis of Host Factors that Contribute to Aging PathogenesisK99AG049092 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MENACHERY, VINEET D · 2015 to 2016
$203kNIAID NIH HHS R01 AI110700NIAID NIH HHS U19 AI109761NIA NIH HHS K99 AG049092NIA NIH HHS R00 AG049092NIDDK NIH HHS P30 DK065988
Abstract
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unknown. Current evidence suggests that insectivorous bats are likely to be the original source, as several 2c CoVs have been described from various species in the family
Indexed as
PhylogenyVirus AttachmentAnimalsChiropteraEvolution, MolecularGenome, ViralMiddle East Respiratory Syndrome CoronavirusReceptors, VirusSpike Glycoprotein, CoronavirusSyntenyUgandaReceptors, VirusSpike Glycoprotein, CoronavirusbatMERS coronavirusspikeUgandazoonoses
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.