Evidence map›Paper›PMID 28377529›Full record

ArticlemBio2017

Catabolism of the Last Two Steroid Rings in

Adam M Crowe, Israël Casabon, Kirstin L Brown, Jie Liu, Jennifer Lian, Jason C Rogalski, Timothy E Hurst, Victor Snieckus, Leonard J Foster, Lindsay D Eltis

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Degradation of CCurrent microbiology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Exposure ofFrontiers in tuberculosis · 2024
    Article
  12. Comprehensive summary of steroid metabolism inApplied and environmental microbiology · 2023
    Article
  13. Article
  14. Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism inAntimicrobial agents and chemotherapy · 2023
    Article
  15. Article
  16. Current Trends and Perspectives in Microbial Bioconversions of Steroids.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  17. Insight into Different Stages of Steroid Degradation in ThermophilicInternational journal of molecular sciences · 2022
    Article
  18. The unusual convergence of steroid catabolic pathways inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Adam M CroweDepartment of Biochemistry and Molecular Biology, Life Sciences Institute, The University of British Columbia, Vancouver, Canada.
Israël CasabonDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, Canada.
Kirstin L BrownDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, Canada.
Jie LiuDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, Canada.
Jennifer LianDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, Canada.
Jason C RogalskiCentre for High-Throughput Biology (CHiBi), Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, Canada.
Timothy E HurstDepartment of Chemistry, Queen's University, Kingston, Canada.
Victor SnieckusDepartment of Chemistry, Queen's University, Kingston, Canada.
Leonard J FosterCentre for High-Throughput Biology (CHiBi), Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, Canada.
Lindsay D EltisDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, Canada leltis@mail.ubc.ca.
University of British Columbia · CAQueen's University · CA

Funding

CIHR
6 · The paper itself

Abstract

Most mycolic acid-containing actinobacteria and some proteobacteria use steroids as growth substrates, but the catabolism of the last two steroid rings has yet to be elucidated. In

Indexed as

CholesterolGene DeletionMetabolic Networks and PathwaysMetabolismMycobacterium smegmatisMycobacterium tuberculosisRhodococcusCholesterolcatabolismcholesterolCoA thioesterMycobacterium tuberculosisring opening

Identifiers

PMID28377529
PMCPMC5380842
OpenAlexW2605148751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.