Evidence map›Paper›PMID 28377501›Full record

ArticleThe Journal of biological chemistry2017

The transcription factor

Ryan K Mitchell, Marie-Sophie Nguyen-Tu, Pauline Chabosseau, Rebecca M Callingham, Timothy J Pullen, Rebecca Cheung, Isabelle Leclerc, David J Hodson, Guy A Rutter

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 60 citations in OpenAlex.

  1. The history and function of a circular RNA.Nature communications · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. PIMT Controls Insulin Synthesis and Secretion through PDX1.International journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Review
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ryan K MitchellFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Marie-Sophie Nguyen-TuFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Pauline ChabosseauFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Rebecca M CallinghamFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Timothy J PullenFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Rebecca CheungFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
Isabelle LeclercFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
David J HodsonFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom, d.hodson@imperial.ac.uk d.hodson@bham.ac.uk.
Guy A RutterFrom the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom, g.rutter@imperial.ac.uk.
Imperial College London · GBUniversity of Birmingham · GB

Funding

Diabetes UK 12/0004431Medical Research Council GO401641Medical Research Council MR/J0003042/1Medical Research Council MR/K001981/1Medical Research Council MR/N00275X/1Wellcome Trust
6 · The paper itself

Abstract

Heterozygous mutations in the human paired box gene

Indexed as

Calcium SignalingGene Expression RegulationAdenosine TriphosphateAnimalsCalciumGlucoseHumansInsulin-Secreting CellsMiceMice, KnockoutPAX6 Transcription FactorAdenosine TriphosphateCalciumGlucosePax6 protein, mousePAX6 Transcription Factorcalciumdiabetesgene expressionimaginginsulinislet

Identifiers

PMID28377501
PMCPMC5448123
OpenAlexW2605083661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.