Evidence map›Paper›PMID 28376883›Full record

ArticleMalaria journal2017

Asymptomatic and sub-microscopic malaria infection in Kayah State, eastern Myanmar.

Myo Thiha Zaw, Myo Thant, Tin Maung Hlaing, Naing Zin Aung, Min Thu, Kanit Phumchuea, Kanokwan Phusri, Teerawat Saeseu, Ritthideach Yorsaeng, Wang Nguitragool and 4 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Asymptomatic/submicroscopicParasite epidemiology and control · 2025
    Article
  5. [SubmicroscopicMedecine tropicale et sante internationale · 2025
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  15. Understanding Spatiotemporal Human Mobility Patterns for Malaria Control Using a Multiagent Mobility Simulation Model.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Myo Thiha ZawDefence Services Medical Research Centre (DSMRC), Nay Pyi Taw, Myanmar.
Myo ThantDefence Services Medical Research Centre (DSMRC), Nay Pyi Taw, Myanmar.
Tin Maung HlaingDefence Services Medical Research Centre (DSMRC), Nay Pyi Taw, Myanmar.
Naing Zin AungDefence Services Medical Research Centre (DSMRC), Nay Pyi Taw, Myanmar.
Min ThuLoikaw Military Hospital, Loikaw, Kayah, Myanmar.
Kanit PhumchueaMahidol Vivax Research Unit (MVRU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Kanokwan PhusriMahidol Vivax Research Unit (MVRU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Teerawat SaeseuMahidol Vivax Research Unit (MVRU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Ritthideach YorsaengMahidol Vivax Research Unit (MVRU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Wang NguitragoolDepartment of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Ingrid FelgerDepartment of Medical Parasitology and Infection Biology, Swiss Tropical & Public Health Institute, Basel, Switzerland.
Jaranit KaewkungwalDepartment of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Liwang CuiDepartment of Entomology, The Pennsylvania State University, 501 ASI Building, University Park, PA, 16801, USA. luc2@psu.edu.
Jetsumon SattabongkotMahidol Vivax Research Unit (MVRU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. jetsumon.pra@mahidol.ac.th.
Mahidol University · THMyanmar Oxford Clinical Research Unit · MMMahidol Oxford Tropical Medicine Research Unit · THTechnological University Loikaw · MMPennsylvania State University · USSwiss Tropical and Public Health Institute · CH

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
Vivax Malaria culture technique and genetic diversity in ThailandD43TW006571 · FIC · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI CUI, LIWANG · 2004 to 2018
$1.9M
FIC NIH HHS D43 TW006571NIAID NIH HHS U19 AI089672
6 · The paper itself

Abstract

backgroundMyanmar has the heaviest burden of malaria in the Greater Mekong Sub-region. Asymptomatic Plasmodium spp. infections are common in this region and may represent an important reservoir of transmission that must be targeted for malaria elimination.

methodsA mass blood survey was conducted among 485 individuals from six villages in Kayah State, an area of endemic but low transmission malaria in eastern Myanmar. Malaria infection was screened by rapid diagnostic test (RDT), light microscopy and real-time polymerase chain reaction (PCR), and its association with demographic factors was explored.

resultsThe prevalence of asymptomatic Plasmodium spp. infection was 2.3% (11/485) by real-time PCR. Plasmodium vivax accounted for 72.7% (8/11) and Plasmodium falciparum for 27.3% (3/11) of infections. Men were at greater risk of infection by Plasmodium spp. than women. Individuals who worked as farmers or wood and bamboo cutters had an increased risk of infection.

conclusionA combination of RDT, light microscopy and PCR diagnostics were used to identify asymptomatic malaria infection, providing additional information on asymptomatic cases in addition to the routine statistics on symptomatic cases, so as to determine the true burden of disease in the area. Such information and risk factors can improve malaria risk stratification and guide decision-makers towards better design and delivery of targeted interventions in small villages, representative of Kayah State.

Indexed as

Asymptomatic DiseasesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCross-Sectional StudiesDemographyDiagnostic Tests, RoutineFemaleHumansInfantMalariaMaleMass ScreeningAsymptomaticMalariaMyanmarSub-microscopic

Identifiers

PMID28376883
PMCPMC5381021
OpenAlexW2605261330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.