Evidence map›Paper›PMID 28376848›Full record

ArticleBMC research notes2017

Prevalence and pattern of dyslipidemia in Nepalese individuals with type 2 diabetes.

Daya Ram Pokharel, Dipendra Khadka, Manoj Sigdel, Naval Kishor Yadav, Shreedhar Acharya, Ramchandra Kafle, Ravindra Mohan Sapkota, Tara Sigdel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

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  10. Patterns of dyslipidemia and its associated factors among prediabetic subjects. A cross-sectional study at a primary care clinic.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Daya Ram PokharelDepartment of Biochemistry, Manipal College of Medical Sciences, Deep Height, Pokhara-16, Kaski, Nepal. drpokharel09@gmail.com.
Dipendra KhadkaDepartment of Laboratory, School of Health and Allied Sciences, Pokhara University, Dhungepatan, Lekhnath, Kaski, Nepal.
Manoj SigdelDepartment of Biochemistry, Manipal College of Medical Sciences, Deep Height, Pokhara-16, Kaski, Nepal.
Naval Kishor YadavDepartment of Biochemistry, Manipal College of Medical Sciences, Deep Height, Pokhara-16, Kaski, Nepal.
Shreedhar AcharyaAssessment and Evaluation Division, Northern Ontario School of Medicine, 935 Ramsey Lake Road, Sudbury, ON, P3E 2C6, Canada.
Ramchandra KafleDepartment of Internal Medicine, Manipal College of Medical Sciences and Teaching Hospital, Phulbari, Pokhara, Kaski, Nepal.
Ravindra Mohan SapkotaShikhar Biotech Pvt Ltd, Khumaltar, Lalitpur, Nepal.
Tara SigdelDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA, 94017, USA.
Manipal College of Medical Sciences · NPNOSM University · CAPokhara University · NPUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtherogenic dyslipidemia is an important modifiable risk factor for cardiovascular disease among patients of type 2 diabetes mellitus. Timely detection and characterization of this condition help clinicians estimate future risk of cardiovascular disease and take appropriate preventive measures. The aim of this study was to determine the prevalence, pattern and predictors of dyslipidemia in a cohort of Nepalese patients with type 2 diabetes.

resultsWe found mixed dyslipidemia as the most prevalent (88.1%) and isolated dyslipidemia (10.1%) as the least prevalent forms of dyslipidemia in our patients. The most prevalent form of single dyslipidemia was high LDL-C (73.8%) and combined dyslipidemia was high TG, high LDL-C and low HDL-C (44.7%). Prevalence of all single and mixed dyslipidemia was higher in patients with poor glycemic control and hypertension. The glycemic status of patients correlated with their fasting serum lipid profile. Dyslipidemia was associated mainly with male gender, poor glycemic control and hypertension.

conclusionsAtherogenic dyslipidemia is associated mainly with male gender, poor glycemic control and hypertension. It is highly prevalent in Nepalese patients with type 2 diabetes. Urgent lifestyle modification, sustained glycemic control and aggressive lipid lowering treatment plans are necessary to minimize the future risk of cardiovascular disease in this population.

Indexed as

AdultAnalysis of VarianceAtherosclerosisBlood GlucoseCholesterolCholesterol, HDLCholesterol, LDLCohort StudiesComorbidityCross-Sectional StudiesDiabetes Mellitus, Type 2DyslipidemiasFemaleHumansMaleMiddle AgedBlood GlucoseCholesterolCholesterol, HDLCholesterol, LDLTriglyceridesCardiovascular diseaseDyslipidemiaNepalPokharaPrevalenceType 2 diabetes

Identifiers

PMID28376848
PMCPMC5379598
OpenAlexW2604665099

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.