Evidence map›Paper›PMID 28376442›Full record

SynthesisAnnals of family medicine2016

Prevalence of Atypical Pathogens in Patients With Cough and Community-Acquired Pneumonia: A Meta-Analysis.

Christian Marchello, Ariella Perry Dale, Thuy Nhu Thai, Duk Soo Han, Mark H Ebell

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of family medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Global Perspective ofInternational journal of environmental research and public health · 2022
    Pooled it
  3. Frontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Evaluation of three real-time PCR methods for the detection and the differentiation of Bordetella pertussis, Bordetella parapertussis and Bordetella holmesii.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  9. Epidemiology, Characteristics, and Treatment Outcomes ofOpen forum infectious diseases · 2025
    Article
  10. Article
  11. Case Report:Frontiers in pediatrics · 2025
    Article
  12. Sultan Qaboos University medical journal · 2025
    Article
  13. Article
  14. CRP under 130 mg/L rules out the diagnosis of Legionella pneumophila serogroup 1 (URINELLA Study).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Observational
  15. Article
  16. Article
  17. Article
  18. Clinical and Laboratory Diagnosis of Legionella Pneumonia.Diagnostics (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christian MarchelloDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia.
Ariella Perry DaleDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia.
Thuy Nhu ThaiDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia.
Duk Soo HanDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia.
Mark H EbellDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia ebell@uga.edu.
University of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCommunity-acquired pneumonia (CAP), acute cough, bronchitis, and lower respiratory tract infections (LRTI) are often caused by infections with viruses or

methodsWe performed a systematic review of MEDLINE for prospective, consecutive-series studies reporting the prevalence of

resultsFifty studies met our inclusion criteria. While calculated heterogeneity was high, most studies reported prevalence for each pathogen within a fairly narrow range. In patients with CAP, the overall prevalences of

conclusionsAtypical bacterial pathogens are relatively common causes of lower respiratory diseases, including cough, bronchitis, and CAP. Where surveillance data were available, we found higher prevalences in studies where all patients are tested for these pathogens. It is likely that these conditions are underreported, underdiagnosed, and undertreated in current clinical practice.

Indexed as

Bordetella pertussisChlamydophila pneumoniaeCommunity-Acquired InfectionsCoughHumansLegionella pneumophilaMycoplasma pneumoniaePneumonia, BacterialPrevalenceBordetella pertussisChlamydophila pneumoniaecommunity acquired pneumoniacoughLegionella pneumophilaMycoplasma pneumoniaerespiratory tract infection

Identifiers

PMID28376442
PMCPMC5389400
OpenAlexW2549279051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.