Evidence map›Paper›PMID 28376374›Full record

ArticleClinical neurology and neurosurgery2017

Brain MRI findings in patients with idiopathic hypersomnia.

Lynn Marie Trotti, Donald L Bliwise

Abstract read
In one paragraph

Article in Clinical neurology and neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A scoping review of the evidence on pharmacological and nonpharmacological interventions for idiopathic hypersomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lynn Marie TrottiSleep Center and Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: Lbecke2@emory.edu.
Donald L BliwiseSleep Center and Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: dbliwis@emory.edu.

Funding

Sleepiness and sleep drunkenness: narcolepsy versus GABA-related hypersomniaK23NS083748 · NINDS · EMORY UNIVERSITY · PI TROTTI, LYNN MARIE · 2014 to 2018
$918k
NINDS NIH HHS K23 NS083748
6 · The paper itself

Abstract

objectiveProper diagnosis of idiopathic hypersomnia necessitates the exclusion of neurologic or medical causes of sleepiness that better explain the clinical syndrome. However, there are no formal guidelines regarding the use of neuroimaging to identify such secondary causes of symptoms. We sought to characterize brain MRI findings in a series of patients with idiopathic hypersomnia.

methodsWe reviewed medical records on a consecutive series of 61 patients diagnosed with idiopathic hypersomnia to determine the frequency and results of brain magnetic resonance imaging (MRI).

resultsOne-third of patients had undergone brain MRI, with focal neurologic signs or symptoms being the most common indication for neuroimaging. Although seven patients had an identifiable finding on neuroimaging (e.g., chronic microvascular ischemic changes), clinical management was changed as a result of imaging in only three cases. In all three, the imaging finding was predated by clear clinical abnormalities.

conclusionsNeuroimaging may be a complementary part of an idiopathic hypersomnia evaluation, but the decision to pursue imaging should be made on a case-by-case basis.

Indexed as

Magnetic Resonance ImagingAdultAgedBrain StemDiagnosis, DifferentialFemaleHumansIdiopathic HypersomniaMaleMiddle AgedNarcolepsyNeuroimagingHypersomnolenceIdiopathic hypersomniaMagnetic resonance imagingNarcolepsyNeuroimagingSleep disorders

Identifiers

PMID28376374
PMCPMC5493205

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.