Observational studyRetina (Philadelphia, Pa.)2018
SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN MACULA-INVOLVING CYTOMEGALOVIRUS RETINITIS.
Observational study in Retina (Philadelphia, Pa.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Optical coherence tomography biomarkers as outcome predictors to guide dexamethasone implant use in patients with iERM: a randomized controlled trial.BMC ophthalmology · 2024Trial
- When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients.World journal of stem cells · 2025Review
- Overview of Cytomegalovirus Ocular Diseases: Retinitis, Corneal Endotheliitis, and Iridocyclitis.Viruses · 2024Review
- Diffuse retinal dysfunction following immune reconstitution uveitis in patients with prior cytomegalovirus retinitis: a novel observation.Documenta ophthalmologica. Advances in ophthalmology · 2023Article
- Clinical application of optical coherence tomography angiography in diabetic macular edema.African health sciences · 2023Article
- Spectral Domain Optical Coherence Tomography Findings in Vision-Threatening Rhino-Orbital Cerebral Mucor Mycosis-A Prospective Analysis.Diagnostics (Basel, Switzerland) · 2022Article
- Role of multicolour imaging in post-fever retinitis involving posterior pole.International ophthalmology · 2021Article
- Clinical Characteristics Associated with the Development of Cystoid Macular Edema in Patients with Cytomegalovirus Retinitis.Microorganisms · 2021Article
- A novel OCT signature in leukemic papillopathy masquerading as autoimmune or infectious uveitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Macular Structure and Microvasculature Changes in AIDS-Related Cytomegalovirus Retinitis Using Optical Coherence Tomography Angiography.Frontiers in medicine · 2021Article
- Extralesional microvascular and structural macular abnormalities in cytomegalovirus retinitis.Scientific reports · 2020Observational
- Spectral-domain optical coherence tomography finding in cytomegalovirus retinitis in AIDS patients.International journal of ophthalmology · 2020Article
- Abnormal levels of aqueous humor trace elements in patients with cytomegalovirus retinitis.Eye (London, England) · 2019Article
- Article
- Cytomegalovirus retinitis in the post-cART era.Current ophthalmology reports · 2018Article
- An unusual case of presumed cytomegalovirus: retinitis in a non-HIV patient treated for IgG 4-related disease.Arquivos brasileiros de oftalmologiaArticle
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the microstructural features of cytomegalovirus (CMV) retinitis by spectral domain optical coherence tomography (OCT).
methodsSubjects were patients with macula-involving CMV retinitis with OCT imaging. The leading edge of retinitis in the macula was identified based on fundus imaging, and OCT findings were longitudinally evaluated in three areas: within the area of active retinitis, at the leading edge of retinitis, and just beyond the leading edge of retinitis.
resultsOptical coherence tomography imaging of macular CMV retinitis identified vitreous cells in 10 eyes (100%), posterior vitreous detachment in four eyes (40%), broad-based vitreomacular traction in one eye (10%), epiretinal membrane in eight eyes (80%), and lamellar hole-associated epiretinal proliferation associated with an atrophic hole in one eye (10%). Retinal architectural disruption, disruption of inner retinal layers, disruption of the external limiting membrane, and ellipsoid zone abnormalities were noted within the area of retinitis in all eyes and decreased in frequency and severity at and beyond the leading edge of retinitis, although all 10 eyes (100%) exhibited one of these abnormalities, especially outer retinal microabnormalities, beyond the leading edge of retinitis.
conclusionMicrostructural abnormalities were frequently noted on OCT of CMV retinitis, including within the retina beyond the leading edge of retinitis identified by corresponding fundus imaging. Outer retinal abnormalities were noted more frequently than inner retinal abnormalities beyond the leading edge of retinitis. These findings provide insight into the effects of CMV retinitis on retinal microstructure and potentially on vision and highlight the potential utility of OCT for monitoring microprogression of macula-involving CMV retinitis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.